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Gastroenterology
Clinical implication of serum uric acid level in pegylated interferon and ribavirin combination therapy for chronic hepatitis C infection
In Soo Oh, Joung Won Won, Hyung Joon Kim, Hyun Woong Lee
Korean J Intern Med. 2017;32(6):1010-1017. Published online August 11, 2017
Background/Aims: Combined treatment of pegylated interferon-α (PEG-IFN) and ribavirin (RBV) has long been accepted as the standard treatment for chronic hepatitis C virus (HCV) infection. Many predictive factors for treatment response have been identified. The aim of this study was to evaluate the..
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Infectious diseases
In vitro antiviral activity of ribavirin against severe fever with thrombocytopenia syndrome virus
Myung Jin Lee, Kye-Hyung Kim, Jongyoun Yi, Su Jin Choi, Pyoeng Gyun Choe, Wan Beom Park, Nam Joong Kim, Myoung-don Oh
Korean J Intern Med. 2017;32(4):731-737. Published online November 30, 2016
Background/Aims: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by severe fever with thrombocytopenia syndrome virus (SFTSV), a novel bunyavirus. As yet, there is no effective antiviral therapy for SFTS. Ribavirin is a broad-spectrum antiviral agent, whic..
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Cryptococcal meningitis in a patient with chronic hepatitis C treated with pegylated-interferon and ribavirin
Tae-Hee Lee, Kee-Ook Lee, Yong-Seok Kim, Sun-Moon Kim, Kyu-Chan Huh, Young-Woo Choi, Young-Woo Kang
Korean J Intern Med. 2014;29(3):370-374. Published online April 29, 2014
Various adverse events have been reported during combination therapy with pegylated (PEG)-interferon-α and ribavirin, although opportunistic infections, especially cryptococcal meningitis, are very rare. A 61-year-old woman complained of headaches and a fever during treatment of a chronic hepatiti..
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Assessment of the Efficacy of Reducing Peginterferon Alfa-2a and Ribavirin Dose on Virologic Response in Koreans with Chronic Hepatitis C
Jung Hyun Kwon, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Kwan Soo Byun, Seung Woon Paik, Young Suk Lim, Han Chu Lee, Kwang Hyub Han, Kwan Sik Lee
Korean J Intern Med. 2009;24(3):203-211. Published online August 26, 2009
Background/AimsThe virologic response of Koreans to combination therapy for chronic hepatitis C is similar to westerns; however, dose modification occurs more frequently in Koreans. We evaluated the rates of peginterferon α-2a and ribavirin dose modifications and their effect o..
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