Pulmonology
Real-world evaluation of atezolizumab and etoposide-carboplatin as a first-line treatment for extensive-stage small cell lung cancer
Soo Han Kim, Eun Jung Jo, Jeongha Mok, Kwangha Lee, Ki Uk Kim, Hye-Kyung Park, Min Ki Lee, Jung Seop Eom, Mi-Hyun Kim
Korean J Intern Med. 2023;38(2):218-225. Published online February 21, 2023
Background/Aims: Despite the obvious benefits of adding immune checkpoint inhibitors to platinum-etoposide chemotherapy in patients with extensive-stage small-cell lung cancer (ES-SCLC), real-world data remain scarce.
Methods: This retrospective study included 89 patients with ES-SCLC treated with ..
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Hemato-oncology
Analysis of thromboembolic events in head and neck cancer patients who underwent concurrent chemoradiotherapy with cisplatin
[corrected-article]
Hundo Cho, Jin-Hyuk Choi, Seok Yun Kang, Hyun Woo Lee, Yong Won Choi, Tae-Hwan Kim, Mi Sun Ahn, Chul-Ho Kim, Yoo Seob Shin, Jeon Yeob Jang, Young-Taek Oh, Jaesung Heo, Seung Soo Sheen
Korean J Intern Med. 2022;37(3):653-659. Published online April 20, 2022
Background/Aims: The study investigated the incidence of thromboembolic events (TEE) in head and neck (H&N) cancer patients who received concurrent chemoradiotherapy (CCRT) with cisplatin, and analyzed the factors affecting TEE occurrence
Methods: Two hundred and fifty-seven patients who started CC..
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Induction chemotherapy followed by concurrent chemoradiotherapy versus CCRT for locally
advanced hypopharynx and base of tongue cancer
Sung Hee Lim, Jong-Mu Sun, Joohyun Hong, Dongryul Oh, Yong Chan Ahn, Man Ki Chung, Han-Sin Jeong, Young-Ik Son, Myung-Ju Ahn, Chung-Hwan Baek, Keunchil Park
Korean J Intern Med. 2021;36(Suppl 1):S217-S224. Published online April 3, 2020
Background/Aims: Clinical trials have not consistently supported the use of induction chemotherapy (IC) for locally advanced head and neck squamous cell cancer. Hypopharynx and base of tongue (BOT) cancer has shown relatively poor survival. We investigated the role of IC in improving outcome over c..
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Role of concurrent chemoradiation on locally advanced unresectable adenoid cystic carcinoma
Hyerim Ha, Bhumsuk Keam, Chan-Young Ock, Tae Min Kim, Jin Ho Kim, Eun-Jae Chung, Seong Keun Kwon, Soon-Hyun Ahn, Hong-Gyun Wu, Myung-Whun Sung, Dae Seog Heo
Korean J Intern Med. 2021;36(1):175-181. Published online March 30, 2020
Background/Aims: Adenoid cystic carcinoma (ACC) is a rare salivary gland tumor characterized by indolence, with a high rate of local recurrence and distant metastasis. This study aimed to investigate the effect of concurrent chemoradiation (CCRT) on locally advanced unresectable ACC.
Methods: We re..
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Evaluation of treatment response and tissue necrosis as prognostic indicators following neoadjuvant chemoradiotherapy in rectal cancer patients
Ji-Han Jung, Ho Jung An, Hyung-Jin Kim, Jonghoon Lee, Kang-Moon Lee, Sung Hwan Kim, Hyeon-Min Cho, Byoung Yong Shim
Korean J Intern Med. 2016;31(1):134-144. Published online December 28, 2015
Background/Aims: The objective of this study was to assess the prognostic roles of treatment response and tissue necrosis after chemoradiotherapy (CRT) in locally advanced rectal cancer.
Methods: A total of 243 patients with locally advanced rectal cancer who underwent neoadjuvant CRT were included..
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Long-term survival after concurrent chemoradiation therapy for esophageal cancer with tracheal
invasion
Joon Hyun Cho, Tae Nyeun Kim
Korean J Intern Med. 2015;30(6):931-933. Published online October 30, 2015
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Gastroenterology
Newer treatments for advanced hepatocellular carcinoma
Myeong Jun Song, Si Hyun Bae
Korean J Intern Med. 2014;29(2):149-155. Published online February 27, 2014
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. The only curative treatment modalities for HCC are surgery, percutaneous ablation, and liver transplantation. Unfortunately, the majority of patients have unresectable disease at diagnosis. Therefore, effective treatment opt..
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Pulmonology
The start of chemotherapy until the end of radiotherapy in patients with limited-stage small cell lung cancer
Kyoung Ju Lee, Eun Joo Lee, Gyu Young Hur, Sang Yeub Lee, Je Hyeong Kim, Chol Shin, Jae Jeong Shim, Kwang Ho In, Kyung Ho Kang, Se Hwa Yoo, Sung Yong Lee
Korean J Intern Med. 2013;28(4):449-455. Published online July 1, 2013
Background/AimsChemotherapy combined with radiation therapy is the standard treatment for limited stage small cell lung cancer (LS-SCLC). Although numerous studies indicate that the overall duration of chemoradiotherapy is the most relevant predictor of outcome, the optimal ch..
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Role of Photodynamic Therapy in the Palliation of Obstructing Esophageal Cancer
Hyeon Young Yoon, Young Koog Cheon, Hye Jin Choi, Chan Sup Shim
Korean J Intern Med. 2012;27(3):278-284. Published online September 1, 2012
Background/AimsThe aim of this non-randomized study was to determine the role of photodynamic therapy (PDT) in a multimodal approach for the palliation of advanced esophageal carcinoma. MethodsTwenty consecutive patients with obstructing esophag..
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Application of Helical Tomotherapy for Two Cases of Advanced Hepatocellular Carcinoma
Joon Sung Kim, Chan Ran You, Jeong Won Jang, Si-Hyun Bae, Jong Yong Choi, Seung Kew Yoon, Chul Seung Kay
Korean J Intern Med. 2011;26(2):201-206. Published online June 1, 2011
The role of radiotherapy in the treatment of hepatocellular carcinoma (HCC) has been limited to date, because the liver has a low tolerance to radiation. However, reconstructing tumors and surrounding organs via a three-dimensional conformal planning system can avoid excess radiotherapy exposure ..
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Clinical Characteristics of Pulmonary Embolism with Underlying Malignancy
Ji Eun Lee, Hye-Ryoun Kim, Sang-Min Lee, Jae-Joon Yim, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Young-Soo Shim, Seok-Chul Yang
Korean J Intern Med. 2010;25(1):66-70. Published online February 26, 2010
Background/AimsThe risk of venous thromboembolism (VTE), which encompasses deep vein thrombosis and pulmonary embolism (PE), increases in patients with cancer. Anticancer treatment is also associated with an increased risk for VTE. We conducted this study to investigate the cl..
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Longlasting Remission of Primary Hepatic Mucosa-associated Lymphoid Tissue (MALT) Lymphoma Achieved by Radiotherapy Alone
Sang Yun Shin, Jin Seok Kim, Jong Keun Lim, Jee Sook Hahn, Woo Ick Yang, Chang Ok Suh
Korean J Intern Med. 2006;21(2):127-131. Published online June 30, 2006
Primary hepatic lymphoma is a rare disorder representing less than 1% of all extranodal lymphomas. Histological examination of a primary hepatic lymphoma usually reveals a diffuse large B-cell lymphoma; there have been few reports of primary hepatic mucosa-associated lymphoid tissue (MALT) lympho..
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