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Urgent need for novel antibiotics in Republic of Korea to combat multidrug-resistant bacteria
Hyo-Jin Lee, Dong-Gun Lee
Korean J Intern Med. 2022;37(2):271-280. Published online February 28, 2022
Multidrug resistance in bacteria is an important issue and is increasing in frequency worldwide because of the limitations of therapeutic agents. From 2010 to 2019, 14 new systemic antibiotics received regulatory approval in the United States. However, few new antibiotics have been introduced in Rep..
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Infectious diseases
Evaluation of copper alloys for reducing infection by methicillin resistant Staphylococcus aureus and vancomycin resistant Enterococcus faecium in intensive care unit and in vitro
Sung Im Choi, Mee Soo Chang, Taeeun Kim, Kyung Hwa Chung, Seongman Bae, Sung-Han Kim, Chan Jin Yoon, Young Kyoon Kim, Jun Hee Woo
Korean J Intern Med. 2021;36(5):1204-1210. Published online August 18, 2021
Background/Aims: Multi-drug resistant pathogens are increasing among healthcare-associated infections. It is well known that copper and copper alloys have antimicrobial activity. We evaluated the activity of copper against bacteria in a hospital setting in Korea.
Methods: This study was conducted i..
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Clinical and microbiological factors associated with early patient mortality from methicillin-resistant Staphylococcus aureus bacteremia
Tark Kim, Yong Pil Chong, Ki-Ho Park, Kyung Mi Bang, Su-Jin Park, Sung-Han Kim, Jin-Yong Jeong, Sang-Oh Lee, Sang-Ho Choi, Jun Hee Woo, Yang Soo Kim
Korean J Intern Med. 2019;34(1):184-194. Published online July 6, 2017
Background/Aims: Methicillin-resistant Staphylococcus aureus bacteremia (MRSAB) is a major bloodstream infection with a high mortality rate. Identification of factors associated with early mortality in MRSAB patients would be useful for predicting prognosis and developing new therapeutic opti..
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Clinical significance of methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci colonization in liver transplant recipients
Youn Jeong Kim, Sang Il Kim, Jong Young Choi, Seung Kyu Yoon, Young-Kyoung You, Dong Goo Kim
Korean J Intern Med. 2015;30(5):694-704. Published online August 27, 2015
Background/Aims: Liver transplant patients are at high risk for methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE) colonization. We evaluated patients before and after liver transplant using active surveillance culture (ASC) to assess the prevalence ..
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Drug utilization review of mupirocin ointment in a Korean university-affiliated hospital
Sung Hee Youn, Seung Soon Lee, Sukyeon Kim, Jeong-a Lee, Bum Joon Kim, Jounghee Kim, Hye-kyung Han, Jae-Seok Kim
Korean J Intern Med. 2015;30(4):515-520. Published online June 29, 2015
Background/Aims: Intranasa l mupirocin and chlorhexidine bathing are candidate strategies to prevent healthcare-associated infections caused by methicillin-resistant Staphylococcus aureus (MRSA). In Korea, intranasal mupirocin is not available, and mupirocin ointment, an over-the-counter drug..
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