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Infectious diseases
Adverse drug reactions following treatment of latent tuberculosis infection: a linked national tuberculosis surveillance with claims database
Yu-Seon Jung, Sun-Young Jung, Jae-Eun Lee, Kyungeun Lee, Jae Chol Choi
Korean J Intern Med. 2024;39(6):979-988. Published online October 22, 2024
Background/Aims: Few real-world studies explored factors associated with latent tuberculosis infection (LTBI) treatment-related adverse drug reactions (ADRs). This study evaluate ADRs that lead to the discontinuation of LTBI treatment and identify the associated factors, including age groups and dru..
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Pulmonology
Chest computed tomography scan as an initial diagnostic method for tuberculosis infection detected by mass screening
Dong-Hyun Joo, Hyun Woo Lee, Seo-Young Yoon, Tae Yun Park, Eun Young Heo, Deog Kyeom Kim, Hee Soon Chung, Jung-Kyu Lee
Korean J Intern Med. 2021;36(6):1410-1419. Published online July 15, 2021
Background/Aims: We assessed the diagnostic yield of chest computed tomography (CT) as an initial diagnostic method for patients with a tuberculosis (TB) infection detected by mass screening in a country with an intermediate TB burden.
Methods: A retrospective study was conducted on patients with T..
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QuantiFERON-TB Gold PLUS versus QuantiFERON- TB Gold In-Tube test for diagnosing tuberculosis infection
Soo Han Kim, Kyung-Wook Jo, Tae Sun Shim
Korean J Intern Med. 2020;35(2):383-391. Published online December 26, 2019
Background/Aims: QuantiFERON-TB Gold PLUS (QFT-PLUS) was developed as a new version of the interferon-γ (IFN-γ) release assay that contains an extra antigen tube to elicit a CD8+ T-cell response in addition to a CD4+ T-cell response. This study aimed to evaluate the performances of QFT-PLUS versus..
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Latent tuberculosis infection: recent progress and challenges in South Korea
Doosoo Jeon
Korean J Intern Med. 2020;35(2):269-275. Published online February 28, 2020
Management of latent tuberculosis infection (LTBI) is a critical element in the elimination of tuberculosis (TB). However, the low positive predictive value of the current diagnostic tests and the low acceptance and completion rate of the isoniazid- based regimen are major barriers to the implementa..
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Rheumatology
Systemic review: agreement between the latent tuberculosis screening tests among patients with rheumatic diseases
Junhee Pyo, Soo-Kyung Cho, Dam Kim, Yoon-Kyoung Sung
Korean J Intern Med. 2018;33(6):1241-1251. Published online December 28, 2017
Background/Aims: To estimate the level of agreement and positivity rates of latent tuberculosis infection (LTBI) tests prior to the use of tumor necrosis factor (TNF) inhibitors in relation to underlying rheumatic diseases and endemic tuberculosis levels.
Methods: The Ovid-Medline, Embase, and Coch..
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Isoniazid treatment for latent tuberculosis infection is tolerable for rheumatoid arthritis patients receiving tumor necrosis factor inhibitor therapy
Yoon-Kyoung Sung, Soo-Kyung Cho, Dam Kim, Soyoung Won, Chan-Bum Choi, Tae-Hwan Kim, Jae-Bum Jun, Dae-Hyun Yoo, Sang-Cheol Bae
Korean J Intern Med. 2018;33(5):1016-1024. Published online March 13, 2017
Background/Aims: To evaluate the impact of isoniazid (INH) treatment for latent tuberculosis infection (LTBI) on the development of liver function test (LFT) abnormality and the persistence of tumor necrosis factor (TNF) inhibitors in rheumatoid arthritis (RA) patients.
Methods: We retrospectively ..
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Pulmonology
Comparing tuberculin skin test and interferon γ release assay (T-SPOT.TB) to diagnose latent tuberculosis infection in household contacts
Hyun Woo Lee, Yeon Joo Lee, Se Joong Kim, Jong Sun Park, Young-Jae Cho, Ho Il Yoon, Choon-Taek Lee, Jae-Ho Lee
Korean J Intern Med. 2017;32(3):486-496. Published online January 24, 2017
Background/Aims: The tuberculin skin test (TST) and interferon γ release assay are currently used as diagnostic tools to detect latent tuberculosis (TB) infection; however, there are inconsistencies about the degree of agreement between the tests. We aimed to evaluate the concordance rate between ..
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Everolimus-induced activation of latent Mycobacterium tuberculosis infection in a patient with metastatic renal cell carcinoma
So-Yeon Jeon, Ho-Young Yhim, Na-Ri Lee, Eun-Kee Song, Jae-Yong Kwak, Chang-Yeol Yim
Korean J Intern Med. 2017;32(2):365-368. Published online February 2, 2016
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Pulmonology
A prospective cohort study of latent tuberculosis in adult close contacts of active pulmonary tuberculosis patients in Korea
Sun Hyo Park, Seung Jun Lee, Yu Ji Cho, Yi Yeong Jeong, Ho Cheol Kim, Jong Deog Lee, Hee Jin Kim, Dick Menzies
Korean J Intern Med. 2016;31(3):517-524. Published online April 7, 2016
Background/Aims: The objective of this prospective study was to evaluate the diagnosis and treatment of latent tuberculosis infection (LTBI) in adult close contacts of active pulmonary tuberculosis (TB) patients in Korea.
Methods: Adult close contacts of active pulmonary TB patients were recruited ..
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Rheumatology
Poor agreement between QuantiFERON-TB
Gold test and tuberculin skin test results for the
diagnosis of latent tuberculosis infection in
rheumatoid arthritis patients and healthy controls
Joo-Hyun Lee, Hae Sook Sohn, Jin Ho Chun, Hyoun-Ah Kim, Chang Hee Suh, Yun Woo Lee, Bo Young Yoon
Korean J Intern Med. 2014;29(1):76-84. Published online January 2, 2014
Background/Aims: We investigated the agreement between the QuantiFERON-
TB Gold (QFT‑Gold) test and the tuberculin skin test (TST) in the diagnosis
of latent tuberculosis infection in patients with rheumatoid arthritis (RA), compared
with healthy controls, in Korea.
Methods: We recruited 64 pa..
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