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Rheumatology
Association between oral health and hyperuricemia in Korean adults: Korea National Health and Nutrition Examination Survey 2016–2019
Junyong Park, Minkook Son, Sung Won Lee, Won Tae Chung, Sang Yeob Lee
Korean J Intern Med. 2024;39(6):1001-1010. Published online October 22, 2024
Background/Aims: Hyperuricemia plays an essential role in the gout. Despite the clinical significance of hyperuricemia, a direct relationship between oral health and hyperuricemia has not been established. We aim to investigate the association between oral health and hyperuricemia.
Methods: We sele..
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Current state and prospects of gout treatment in Korea
Eun Hye Park, Sang Tae Choi, Jung Soo Song
Korean J Intern Med. 2022;37(4):719-731. Published online June 3, 2022
Effective management of gout includes the following: appropriate control of gout flares; lifestyle modifications; management of comorbidities; and long-term urate-lowering therapy (ULT) to prevent subsequent gout flares, structural joint damage, and shortening of life expectancy. In addition to trad..
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Rheumatology
Distribution of serum uric acid levels and prevalence of hyper- and hypouricemia in a Korean general population of 172,970
Bon San Koo, Hye-Jin Jeong, Chang-Nam Son, Sang-Hyon Kim, Hyun Jung Kim, Gheun-Ho Kim, Jae-Bum Jun
Korean J Intern Med. 2021;36(Suppl 1):S264-S272. Published online November 24, 2020
Background/Aims: We investigated the distribution of serum uric acid (SUA) levels and estimated the prevalence of hyperuricemia and hypouricemia in the Korean population.
Methods: This cross-sectional study used data from the Korean Genome and Epidemiology Study and included 172,970 participants (5..
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Role of asymptomatic hyperuricemia in the progression of chronic kidney disease and cardiovascular disease
Yousuf Waheed, Fan Yang, Dong Sun
Korean J Intern Med. 2021;36(6):1281-1293. Published online July 8, 2021
Previous research has investigated whether hyperuricemia serves as an independent risk factor for cardiovascular and renal diseases. Hyperuricemia is defined as an abnormally high level of uric acid (UA; i.e., serum urate level > 6.8 mg/dL). Hyperuricemia has been considered a complication of chroni..
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Rheumatology
Pilot study: asymptomatic hyperuricemia patients with obesity and nonalcoholic fatty liver disease have increased risk of double contour sign
Hong Ki Min, Hyonjoung Cho, Sung-Hwan Park
Korean J Intern Med. 2020;35(6):1517-1523. Published online June 13, 2019
Background/Aims: Double contour sign (DCS) is a representative ultrasonographic finding in gout. DCS is evidence of monosodium urate deposit in gouty arthritis and has been identified in some patients with asymptomatic hyperuricemia. However, the specific characteristics of asymptomatic hyperuricemi..
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Renal effects of uric acid: hyperuricemia and hypouricemia
Jung Hwan Park, Yong-Il Jo, Jong-Ho Lee
Korean J Intern Med. 2020;35(6):1291-1304. Published online September 9, 2020
The prevalence of chronic kidney disease (CKD) is increasing worldwide. Although hyperuricemia has been associated with CKD in many studies, it remains controversial whether this is the cause or the result of decreased renal function. Recent observational studies of healthy populations and patients ..
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Rheumatology
Clinical features and recurrent attack in gout patients according to serum urate levels during an acute attack
Jung Sun Lee, Oh Chan Kwon, Ji Seon Oh, Yong-Gil Kim, Chang-Keun Lee, Bin Yoo, Seokchan Hong
Korean J Intern Med. 2020;35(1):240-248. Published online January 28, 2019
Background/Aims: A substantial portion of gout patients have normal serum urate levels during an acute attack but data on the clinical characteristics and risk of recurrence compared with hyperuricemic patients are limited. Methods: In this retrospective cohort study, clinical features of normourice..
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Effect of Fenofibrate in Combination with Urate Lowering Agents in Patients with Gout
You-Hyun Lee, Chan-Hee Lee, Jisoo Lee
Korean J Intern Med. 2006;21(2):89-93. Published online June 30, 2006
BackgroundTo assess the efficacy of fenofibrate treatment in combination with urate lowering agents in patients with gout. MethodsFourteen male patients with chronic tophaceous or recurrent acute attacks of gout were evaluated in an open-label p..
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