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Nephrology / Original Article
Assessment of nephrotoxicity of herbal medicine containing aristolochic acid in mice
Yi Quan, Long Jin, Kang Luo, Jian Jin, Sun Woo Lim, Yoo Jin Shin, Eun Jeong Ko, Byung Ha Chung, Chul Woo Yang
Korean J Intern Med. 2020;35(2):400-407. Published online November 21, 2019
Background/Aims: It is undetermined if herbal medicines (HM) containing aristolochic acid (AA)-containing have similar nephrotoxicity to AA itself.
Methods: We administered HM containing a high concentration of AA for 5 days (short-term study) or a low concentration of AA for 30 days (long-term stu..
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Pulmonology / Original Article
HL301 in the treatment of acute bronchitis: a phase 2b, randomized, double-blind, placebocontrolled, multicenter study
Sang Won Yoon, Myung Jae Park, Chin Kook Rhee, Joo Hun Park, Sang Yeub Lee, Do Jin Kim, Dong Gyu Kim, Jae Yeol Kim
Korean J Intern Med. 2020;35(1):133-141. Published online April 9, 2019
Background/Aims: There is insufficient quality data to recommend the use of herbs for the treatment of acute bronchitis. Small number of randomized trials of plant extracts for this purpose were determined to be low quality and there are concerns for the safety. HL301 is a combined product of seven ..
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Nephrology / Original Article
Update of aristolochic acid nephropathy in Korea
Tae Hyun Ban, Ji-Won Min, Changhwan Seo, Da Rae Kim, Yu Ho Lee, Byung Ha Chung, Kyung-Hwan Jeong, Jae Wook Lee, Beom Seok Kim, Sang-Ho Lee, Bum Soon Choi, Jin Suk Han, Chul Woo Yang
Korean J Intern Med. 2018;33(5):961-969. Published online March 20, 2018
Background/Aims: The true incidence of aristolochic acid nephropathy (AAN) is thought to be underestimated because numerous ingredients known or suspected to contain aristolochic acid (AA) are used in traditional medicine in Korea.
Methods: We collected data on cases of AAN since 1996 via a databas..
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Original Article
Effects of Add-On Therapy with NDC-052, an Extract from Magnoliae Flos, in Adult Asthmatic Patients Receiving Inhaled Corticosteroids
Chan Sun Park, Tae-Bum Kim, Jae-Young Lee, Jae Yong Park, Yong Chul Lee, Seong Su Jeong, Yang Deok Lee, You Sook Cho, Hee-Bom Moon
Korean J Intern Med. 2012;27(1):84-90. Published online February 28, 2012
Background/AimsThere is a need for new anti-asthmatic medications with fewer side effects. NDC-052, an extract of the medicinal herb Magnoliae flos, which has a long history of clinical use, was recently found to have anti-inflammatory effects. Herein, we eval..
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Case Report
A Case of Green Urine after Ingestion of Herbicides
Yun-Suk Shim, Hyo-Wook Gil, Jong-Oh Yang, Eun-Young Lee, Soo-Hyun Kim, Sae-Yong Hong
Korean J Intern Med. 2008;23(1):42-44. Published online March 20, 2008
The development of discolored urine may have many possible causes. Here we present the case of a 76-year-old woman who was admitted after ingesting the inorganic herbicides, mefenacet and imazosulfuron. Her urine color changed to green almost immediately. Since the patient had no specific medicat..
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