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Gastroenterology
Additive effect of probiotics (Mutaflor) on 5-aminosalicylic acid therapy in patients with ulcerative colitis
Soo-Kyung Park, Sang-Bum Kang, SangSoo Kim, Tae Oh Kim, Jae Myung Cha, Jong Pil Im, Chang Hwan Choi, Eun Soo Kim, Geom Seog Seo, Chang Soo Eun, Dong Soo Han, Dong Il Park
Korean J Intern Med. 2022;37(5):949-957. Published online March 31, 2022
Background/Aims: In ulcerative colitis (UC) patients, Escherichia coli Nissle 1917 (EcN) is equivalent to mesalazine for preventing disease relapse; however, evidence of the ability of EcN to increase health-related quality of life or induce remission remains scarce. We investigated the efficacy of ..
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Infectious diseases
Cancer patients with neutropenic septic shock: etiology and antimicrobial resistance
Sung Min Jung, Youn Jung Kim, Seung Mok Ryoo, Chang Hwan Sohn, Dong Woo Seo, Kyoung Soo Lim, Won Young Kim
Korean J Intern Med. 2020;35(4):979-987. Published online October 28, 2019
Background/Aims: Among patients with febrile neutropenia that developed after chemotherapy, high-risk patients, such as those having clinical instability or Multinational Association of Supportive Care in Cancer score of < 21, require hospitalization for intravenous empiric antibiotic therapy. Mono..
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Gastroenterology
Infection of human intestinal epithelial cells by invasive bacteria activates NF-κB and increases ICAM-1 expression through NOD1
Woon Geon Shin, Bum Joon Park, Sung Joong Lee, Jae Gyu Kim
Korean J Intern Med. 2018;33(1):81-90. Published online January 16, 2017
Background/Aims: Nucleotide-binding oligomerization domain 1 (NOD1) is required for primary intestinal epithelial cells (IECs) to respond to natural mucopeptides secreted by gram-negative bacteria. Infection of human IECs with invasive bacteria up-regulates intercellular adhesion molecule-1 (ICAM-1)..
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The clinical usefulness of serum procalcitonin level in patients with scrub typhus
Chang-Seop Lee, Jeong-Hwan Hwang, Jeong-Mi Lee, Jae Hoon Lee
Korean J Intern Med. 2017;32(4):761-763. Published online February 4, 2016
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Infectious diseases
Risk factors and molecular epidemiology of community-onset, multidrug resistance extended-spectrum β-lactamase-producing Escherichia coli infections
So Yeon Park, Cheol-In Kang, Yu Mi Wi, Doo Ryeon Chung, Kyong Ran Peck, Nam-Yong Lee, Jae-Hoon Song
Korean J Intern Med. 2017;32(1):146-157. Published online April 20, 2016
Background/Aims: Although multidrug resistance (MDR) among extended-spectrum β-lactamase-producing Escherichia coli (ESBL-EC) poses significant therapeutic challenges, little is known regarding the risk factors and epidemiology of community-onset MDR‑ESBL‑EC infections. We performed this study t..
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Comparative study on the epidemiological aspects of enterohemorrhagic Escherichia coli infections between Korea and Japan, 2006 to 2010
Won-Chang Lee, Young Hwan Kwon
Korean J Intern Med. 2016;31(3):579-584. Published online February 18, 2016
Background/Aims: To compare the epidemiological aspects of enterohemorrhagic Escherichia coli (EHEC) between Korea and Japan by analyzing the current state of EHEC infection outbreaks and related risk factors.
Methods: We investigated the epidemiological aspects of EHEC infection cases betwe..
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Use of cefuroxime for women with community-onset acute pyelonephritis caused by cefuroxime-susceptible or -resistant Escherichia coli
U-Im Chang, Hyung Wook Kim, Seong-Heon Wie
Korean J Intern Med. 2016;31(1):145-155. Published online December 28, 2015
Background/Aims: Efforts to decrease the use of extended-spectrum cephalosporins are required to prevent the selection and transmission of multi-drug resistant pathogens, such as extended-spectrum b-lactamase (ESBL)-producing Enterobacteriaceae. The objectives of this study were to assess the clinic..
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Third-generation cephalosporin resistance of community-onset Escherichia coli and Klebsiella pneumoniae bacteremia in a secondary hospital
Shinwon Lee, Seung Woo Han, Kun Woo Kim, Do young Song, Ki Tae Kwon
Korean J Intern Med. 2014;29(1):49-56. Published online January 2, 2014
Background/Aims: To enable appropriate antimicrobial treatment for community-
onset infections in emergency departments (EDs), data are needed on the
resistance profiles of Escherichia coli and Klebsiella pneumoniae, which are the main
pathogens of community-onset bacteremia.
Methods: Records we..
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