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Hemato-oncology / Review
Germline DDX41 mutations in myeloid neoplasms: a comprehensive review
Je-Hwan Lee, Eun-Hye Hur, Young-Uk Cho
Korean J Intern Med. 2026;41(3):396-410. Published online May 1, 2026
DEAD-box helicase 41 (DDX41)-associated myeloid neoplasms represent a distinct hereditary cancer syndrome and have emerged as the most common form of genetic predisposition to adult-onset hematologic malignancies, accounting for 3–5% of adults with myelodysplastic syndrome and acute myeloid..
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