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Hemato-oncology
Surtuin 1 as a potential prognostic biomarker in very elderly patients with colorectal cancer
Guk Jin Lee, Yun Hwa Jung, Tae-Jung Kim, Yosep Chong, Seo-Won Jeong, In Kyu Lee, In Sook Woo
Korean J Intern Med. 2021;36(Suppl 1):S235-S244. Published online July 2, 2020
Background/Aims: Colorectal cancer (CRC) rate increases with aging. Aging-related proteins, such as sirtuins (SIRTs) may be a potential therapeutic target in the elderly patients with CRC. The clinical implications of SIRT1 and SIRT2 have not been reported for elderly patients with cancer. The aim of..
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Clinical characteristics and treatment propensity in elderly patients aged over 80 years with colorectal cancer
Yun Hwa Jung, Jae Young Kim, Yu Na Jang, Sang Hoon Yoo, Gyo Hui Kim, Kang Min Lee, In Kyu Lee, Su Mi Chung, In Sook Woo
Korean J Intern Med. 2018;33(6):1182-1193. Published online November 24, 2017
Background/Aims: Elderly patients (≥ 80 years) with colorectal cancer (CRC) tend to avoid active treatment at the time of diagnosis despite of recent advances in treatment. The aim of this study was to determine treatment propensity of elderly patients aged ≥ 80 years with CRC in clinical practice ..
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Metronomic chemotherapy with capecitabine for metastatic colorectal cancer in very elderly patients
Yun Hwa Jung, Won Jik Lee, Jae Ho Byeon, In Kyu Lee, Chi Wha Han, In Sook Woo
Korean J Intern Med. 2017;32(5):926-929. Published online March 10, 2016
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Microarray Analysis of Papillary Thyroid Cancers in Korean
Hyun Sook Kim, Do Hyung Kim, Ji Yeon Kim, Nam Ho Jeoung, In Kyu Lee, Jin Gu Bong, Eui Dal Jung
Korean J Intern Med. 2010;25(4):399-407. Published online November 27, 2010
Background/AimsPapillary thyroid cancer (PTC) is the most common malignancy of the thyroid gland. It involves several molecular mechanisms. The BRAF V600E mutation has been identified as the most common genetic abnormality in PTC. Moreover, it is known to be m..
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Novel LMNA Gene Mutation in a Patient With Atypical Werner's Syndrome
Yun Jeong Doh, Hee Kyoung Kim, Eui Dal Jung, Seung Hee Choi, Jung Guk Kim, Bo Wan Kim, In Kyu Lee
Korean J Intern Med. 2009;24(1):68-72. Published online March 6, 2009
Hutchinson-Gilford progeria syndrome (HGPS) and Werner's syndrome are representative types of progeroid syndrome. LMNA (Lamin A/C) gene mutation with atypical Werner's syndrome have recently been reported. Atypical Werner's syndrome with the severe metabolic complications, the ex..
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The Effect of Parental Imprinting on the INS - IGF2 Locus of Korean Type I Diabetic Patients
Heung Sik Kim, Dong Wook Lee, Sang Jun Lee, Bo Hwa Choi, Sung Ik Chang, Hyun Dae Yoon, In Kyu Lee
Korean J Intern Med. 2001;16(4):223-229. Published online December 1, 2001
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