Infectious diseases
Impact of the coronavirus disease 2019 pandemic on the incidence of other infectious diseases in the hematology hospital in Korea
Seohee Oh, Yu-Sun Sung, Mihee Jang, Yong-Jin Kim, Hyun-Wook Park, Dukhee Nho, Dong-Gun Lee, Hyeon Woo Yim, Sung-Yeon Cho
Korean J Intern Med. 2024;39(3):513-523. Published online April 23, 2024
Background/Aims: Since the coronavirus disease 2019 (COVID-19) outbreak, hospitals have implemented infection control measures to minimize the spread of the virus within facilities. This study aimed to investigate the impact of COVID-19 on the incidence of healthcare-associated infections (HCAIs) an..
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Implementing antimicrobial stewardship: lessons and perspectives from a university-affiliated tertiary hospital in Korea
Soo Jin Lee, Raeseok Lee, Sung-Yeon Cho, Dukhee Nho, Hye Lim Ahn, Dong-Gun Lee
Korean J Intern Med. 2024;39(3):399-412. Published online April 30, 2024
Antimicrobial stewardship programs (ASPs) can lower antibiotic use, decrease medical expenses, prevent the emergence of resistant bacteria, and enhance treatment for infectious diseases. This study summarizes the stepwise implementation and effects of ASPs in a single university-affiliated tertiary ..
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Infectious diseases
Risk factors and clinical impact of COVID-19-associated pulmonary aspergillosis: Multicenter retrospective cohort study
Raeseok Lee, Sung-Yeon Cho, Dong-Gun Lee, Hyojin Ahn, Hyeah Choi, Su-Mi Choi, Jae-Ki Choi, Jung-Hyun Choi, Shin Young Kim, Youn Jeong Kim, Hyo-Jin Lee
Korean J Intern Med. 2022;37(4):851-863. Published online May 26, 2022
Background/Aims: The risk factors and clinical impacts of coronavirus disease 2019 (COVID-19)-associated pulmonary aspergillosis (CAPA) remain controversial, and no data have been reported in Korea. This study aimed to investigate the epidemiology and importance of CAPA diagnostic efforts and to ide..
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Urgent need for novel antibiotics in Republic of Korea to combat multidrug-resistant bacteria
Hyo-Jin Lee, Dong-Gun Lee
Korean J Intern Med. 2022;37(2):271-280. Published online February 28, 2022
Multidrug resistance in bacteria is an important issue and is increasing in frequency worldwide because of the limitations of therapeutic agents. From 2010 to 2019, 14 new systemic antibiotics received regulatory approval in the United States. However, few new antibiotics have been introduced in Rep..
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Infectious diseases
Infectious complications after hematopoietic stem cell transplantation: current status and future perspectives in Korea
Sung-Yeon Cho, Hyeon-Jeong Lee, Dong-Gun Lee
Korean J Intern Med. 2018;33(2):256-276. Published online February 27, 2018
Hematopoietic stem cell transplantation (HSCT) is a treatment for hematologic malignancies, immune deficiencies, or genetic diseases, ect. Recently, the number of HSCTs performed in Korea has increased and the outcomes have improved. However, infectious complications account for most of the morbidit..
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Amikacin therapy for urinary tract infections caused by extended-spectrum β-lactamase-producing Escherichia coli
Sung-Yeon Cho, Su-Mi Choi, Sun Hee Park, Dong-Gun Lee, Jung-Hyun Choi, Jin-Hong Yoo
Korean J Intern Med. 2016;31(1):156-161. Published online December 28, 2015
Background/Aims: The number of urinary tract infections (UTIs) caused by extended-spectrum β-lactamase-producing Escherichia coli (ESBL-EC) is increasing. In an outpatient setting, there are limited therapeutic options to treat ESBL-producing pathogens. We evaluated the outcomes of amikacin..
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Cytomegalovirus appendicitis with concurrent bacteremia after chemotherapy for acute leukemia
Min Jung Cho, Jongmin Lee, Joo-Yeun Hu, Jung Woo Lee, Sung-Yeon Cho, Dong-Gun Lee, Seok Lee
Korean J Intern Med. 2014;29(5):675-678. Published online August 28, 2014
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Gastroenterology
Clinical characteristics and the usefulness of the QuantiFERON-TB Gold In-Tube test in hematologic patients with hepatic or splenic lesions
Jae-Cheol Kwon, Si-Hyun Kim, Sun Hee Park, Su-Mi Choi, Dong-Gun Lee, Jung-Hyun Choi, Jin-Hong Yoo, Yoo-Jin Kim, Seok Lee, Hee-Je Kim, Seok-Goo Cho, Jong-Wook Lee, Woo-Sung Min
Korean J Intern Med. 2013;28(2):187-196. Published online February 27, 2013
Background/AimsHepatic or splenic lesions in hematologic patients are not defined well because they are not easy to evaluate due to limitations of invasive procedures. Management typically depends on the clinical diagnosis with few microbiological data. Me..
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Nododuodenal Fistula Caused by Tuberculosis
Dong-Gun Lee, Gwang-Ha Kim
Korean J Intern Med. 2011;26(4):477-477. Published online November 28, 2011
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Evidence-Based Guidelines for Empirical Therapy of Neutropenic Fever in Korea
Dong-Gun Lee, Sung-Han Kim, Soo Young Kim, Chung-Jong Kim, Wan Beom Park, Young Goo Song, Jung-Hyun Choi
Korean J Intern Med. 2011;26(2):220-252. Published online June 1, 2011
Neutrophils play an important role in immunological function. Neutropenic patients are vulnerable to infection, and except fever is present, inflammatory reactions are scarce in many cases. Additionally, because infections can worsen rapidly, early evaluation and treatments are especially importa..
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Clinical Significance of Anaerobic Infections
Dong-Gun Lee
Korean J Intern Med. 2009;24(1):11-12. Published online March 6, 2009
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Intravenous Itraconazole vs. Amphotericin B Deoxycholate for Empirical Antifungal Therapy in Patients with Persistent Neutropenic Fever
Sun Hee Park, Su-Mi Choi, Dong-Gun Lee, Jung-Hyun Choi, Jin-Hong Yoo, Woo-Sung Min, Wan-Shik Shin
Korean J Intern Med. 2006;21(3):165-172. Published online September 30, 2006
BackgroundAmphotericin B dexoycholate is currently the standard empirical antifungal therapy for neutropenic patients with hematologic malignancies and who also have persistent fever that does not respond to antibacterial therapy. The antifungal triazoles offer a potentially s..
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