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Gastroenterology
Analysis of the gut microbiome using extracellular vesicles in the urine of patients with colorectal cancer
Hyuk Yoon, Nam-Eun Kim, Jihye Park, Cheol Min Shin, Nayoung Kim, Dong Ho Lee, Jae Yong Park, Chang Hwan Choi, Jae Gyu Kim, Young Soo Park
Korean J Intern Med. 2023;38(1):27-38. Published online November 10, 2022
Background/Aims: We evaluated the gut microbiome using extracellular vesicles (EVs) in the urine of patients with colorectal cancer (CRC) to determine whether gut-microbe-derived EVs could be a potential biomarker for the diagnosis of CRC.
Methods: EVs were isolated from the urine of patients with ..
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The effect of rebamipide on non-steroidal anti-inflammatory drug-induced gastro-enteropathy: a multi-center, randomized pilot study
Dong Jun Oh, Hyuk Yoon, Hyun Soo Kim, Yoon Jin Choi, Cheol Min Shin, Young Soo Park, Nayoung Kim, Dong Ho Lee, You-Jung Ha, Eun Ha Kang, Yun Jong Lee, Nayoung Kim, Ki-Jeoung Kim, Fei Liu
Korean J Intern Med. 2022;37(6):1153-1166. Published online November 1, 2022
Background/Aims: Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly-used medications, and ailments such as arthritis or heart disease, require long-term use of these drugs, which can induce gastroenteropathy with bleeding and ulcers. This study investigated the associations between efficacy..
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Long-term effect of the eradication of Helicobacter pylori on the hemoglobin A1c in type 2 diabetes or prediabetes patients
Won Seok Kim, Yonghoon Choi, Nayoung Kim, Seon Hee Lim, Gitark Noh, Ki Wook Kim, Jaehyung Park, Hyeongho Jo, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Dong Ho Lee
Korean J Intern Med. 2022;37(3):579-590. Published online January 7, 2022
Background/Aims: The long-term effect of Helicobacter pylori eradication on the metabolic syndrome or diabetes are unclear. The aim of this study was to evaluate the effect of H. pylori eradication on glycemic control in type 2 diabetes mellitus (T2DM) or prediabetes mellitus (preDM).
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Comparison of loss of response between anti-tumor necrosis factor alone and combined use with immunomodulators in patients with inflammatory bowel disease
Seung Wook Hong, Jaewoo Park, Hyuk Yoon, Hye Ran Yang, Cheol Min Shin, Young Soo Park, Nayoung Kim, Dong Ho Lee, Joo Sung Kim
Korean J Intern Med. 2021;36(Suppl 1):S9-S17. Published online June 25, 2020
Background/Aims: Combination therapy with immunomodulators (IMMs) was proposed as a strategy to prevent the development of loss of response (LOR) to anti-tumor necrosis factor (TNF) for patients with inflammatory bowel disease (IBD). However, the effect is unclear in patients already exposed to IMMs..
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Sex difference in bowel preparation quality and colonoscopy time
Young-Jae Hwang, Dong Woo Shin, Nayoung Kim, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Dong Ho Lee
Korean J Intern Med. 2021;36(2):322-331. Published online June 22, 2020
Background/Aims: The length of colon is known to be longer in females than in males. In addition, the morphology of colon cancer is different between males and females. The aim of this study was to investigate sex differences in Boston bowel preparation score (BBPS) and colonoscopy insertion time.
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Association between high fatty liver index and development of colorectal cancer: a nationwide cohort study with 21,592,374 Korean
Yoon Jin Choi, Dong Ho Lee, Kyung-Do Han
Korean J Intern Med. 2020;35(6):1354-1363. Published online April 10, 2020
Background/Aims: In Korea, the incidence of colorectal cancer (CRC) and nonalcoholic fatty liver disease (NAFLD) has increased due to a westernized lifestyle. This study investigated whether a high fatty liver index that reflects NAFLD correlates with CRC.
Methods: Data from the National Health Ins..
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Clinical features of snoring patients during sedative endoscopy
Jung Wha Chung, Nayoung Kim, Jee Hye Wee, Jaebong Lee, Jongchan Lee, Soohoon Kwon, Young-Jae Hwang, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Dong Ho Lee, Jin-Wook Kim
Korean J Intern Med. 2019;34(2):305-314. Published online November 15, 2017
Background/Aims: Snoring is the sound of turbulence and vibration of the upper respiratory tissues and has been identified as a risk factor of obstructive sleep apnea (OSA) and cardiovascular disease. The aim of this study was to identify associated clinical factors in snoring patients undergoing se..
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Development, validation, and application of a novel tool to measure disease-related knowledge in patients with inflammatory bowel disease
Hyuk Yoon, Suk-Kyun Yang, Hoonsub So, Ko Eun Lee, Sang Hyoung Park, Sung-Ae Jung, Joong Haeng Choh, Cheol Min Shin, Young Soo Park, Nayoung Kim, Dong Ho Lee
Korean J Intern Med. 2019;34(1):81-89. Published online November 29, 2017
Background/Aims: The Crohn’s and Colitis Knowledge (CCKNOW) score does not reflect updated knowledge relating to inflammatory bowel disease (IBD). The aim of this study was to develop, validate, and apply a novel tool to measure disease-related knowledge in IBD patients.
Methods: A questionnaire ..
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Clinical outcome of acute nonvariceal upper gastrointestinal bleeding after hours: the role of urgent endoscopy
Dong-Won Ahn, Young Soo Park, Sang Hyub Lee, Cheol Min Shin, Jin-Hyeok Hwang, Jin-Wook Kim, Sook-Hyang Jeong, Nayoung Kim, Dong Ho Lee
Korean J Intern Med. 2016;31(3):470-478. Published online April 6, 2016
Background/Aims: This study was performed to investigate the clinical role of urgent esophagogastroduodenoscopy (EGD) for acute nonvariceal upper gastrointestinal bleeding (ANVUGIB) performed by experienced endoscopists after hours.
Methods: A retrospective analysis was performed for consecutively ..
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Visualization of Jejunal Bleeding by Capsule Endoscopy in a Case of Eosinophilic Enteritis
Nayoung Kim, Jin-Wook Kim, Jin-Hyeok Hwang, Dong Ho Lee, Hye Seung Lee, Kyoung Ho Lee, Sung-Won Kim
Korean J Intern Med. 2005;20(1):63-67. Published online March 31, 2005
Eosinophilic enteritis is a rare disease characterized by tissue eosinophilia, which can affect different layers of bowel wall. Normally, the disease presents as colicky abdominal pain, and rarely as an acute intestinal obstruction or perforation. In this paper, we report a case of eosinophilic e..
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Hepatopulmonary Syndrome in Poorly Compensated Postnecrotic Liver Cirrhosis by Hepatitis B Virus in Korea
Jae Ho Lee, Dong Ho Lee, Joo Hee Zo, Tae Ho Kim, Kook Lae Lee, Hee Soon Chung, Cheol Ho Kim, Sung Ku Han, Young Soo Sim, Hyo Suk Lee, Yong Bum Yoon, In Sung Song, Chung Yong Kim
Korean J Intern Med. 2001;16(2):56-61. Published online June 1, 2001
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Effects of Long-term Teatment of Captopril and Enalapril on Rat Intestinal Angiotenisin Converting Enzyme Specific Activities
In Sung Song, Kyung Wook Yim, Na Young Kim, Byung Chul Yoon, Dong Ho Lee, Hyun Chae Jung, Chung Yong Kim
Korean J Intern Med. 1994;9(2):67-72. Published online July 1, 1994
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