Korean J Intern Med > Volume 30(5); 2015 > Article |
|
Variable |
Initially colonized |
Not initially colonized |
p valuea | |||
---|---|---|---|---|---|---|
Group 1a (n = 12) | Total (n = 130) | Group 2a (n = 9) | Group 3a (n = 121) | p valueb | ||
Age, yr | 53 (40–61) | 49 (41–56) | 47 (42.5–54.5) | 50 (40–56) | 0.94 | 0.53 |
Male sex | 8 (66.7) | 84 (64.6) | 7 (77.8) | 77 (63.6) | 0.39 | 0.47 |
Underlying liver disease | 0.04 | 0.58 | ||||
Hepatitis B | 6 (50.0) | 69 (53.1) | 4 (44.4) | 65 (53.7) | ||
Hepatitis C | 3 (25.0) | 8 (6.2) | 0 | 8 (6.6) | ||
Hepatitis B + C | 0 | 1 (1.5) | 0 | 1 (0.8) | ||
Hepatitis A | 2 (16.7) | 14 (10.8) | 0 | 14 (11.6) | ||
Cryptogenic cirrhosis | 0 | 5 (3.8) | 0 | 5 (4.1) | ||
Primary biliary cirrhosis | 0 | 1 (0.8) | 0 | 1 (0.8) | ||
Alcoholic liver disease | 1 (8.3) | 18 (13.8) | 1 (11.1) | 17 (14.0) | ||
Others | 0 | 14 (10.7) | 4 (44.4) | 10 (8.3) | ||
Cause of transplantation | ||||||
Decompensated liver cirrhosis | 7 (58.3) | 72 (55.4) | 4 (44.4) | 68 (56.2) | 0.49 | 0.84 |
Fulminant hepatitis | 2 (16.7) | 24 (18.5) | 3 (33.3) | 21 (17.4) | 0.23 | 0.88 |
Hepatocellular carcinoma | 4 (33.3) | 50 (38.5) | 1 (11.1) | 49 (40.5) | 0.08 | 0.73 |
Comorbid condition | ||||||
Diabetes mellitus | 1 (8.3) | 38 (29.2) | 3 (33.3) | 35 (28.9) | 0.78 | 0.12 |
Hypertension | 3 (25) | 14 (10.7) | 1 (11.1) | 13 (10.7) | 0.97 | 0.15 |
Retransplantation | 0 | 4 (3.1) | 2 (22.2) | 2 (1.7) | < 0.01 | 0.53 |
Pretransplant condition | ||||||
MELD score | 21 (12.7–30.7) | 18 (10–30) | 28 (18.5–39.5) | 16 (10–28) | 0.05 | 0.56 |
Child-Pugh, class C | 9 (75.0) | 77 (59.2) | 7 (77.9) | 70 (57.9) | 0.23 | 0.54 |
Pretransplant dialysis | 2 (16.7) | 23 (17.7) | 5 (55.6) | 18 (14.9) | < 0.01 | 0.92 |
Posttransplant condition | ||||||
Reoperation | 1 (8.3) | 17 (13.1) | 3 (33.3) | 14 (11.6) | 0.06 | 0.64 |
Posttransplant dialysis | 4 (36.4) | 18 (14.9) | 1 (12.5) | 17 (15.0) | 0.85 | 0.06 |
Biliary complication | 5 (41.7) | 46 (35.4) | 2 (22.2) | 44 (36.4) | 0.39 | 0.66 |
Invasive device | ||||||
Central venous catheter | 2 (16.7) | 40 (30.8) | 2 (22.2) | 38 (31.4) | 0.56 | 0.67 |
Hemodialysis catheter | 4 (33.3) | 23 (17.7) | 4 (44.4) | 19 (15.7) | 0.03 | 0.18 |
Foley catheter | 6 (50.0) | 41 (31.5) | 2 (22.2) | 39 (32.2) | 0.53 | 0.19 |
Ventilator | 1 (8.3) | 3 (2.3) | 0 | 3 (2.5) | 0.64 | 0.23 |
History of previous hospitalization | 3 (25.0) | 66 (50.8) | 6 (66.7) | 60 (49.6) | 0.32 | 0.08 |
Preoperative hospital stay, day | 18 (4.5–26) | 4 (3–13) | 8 (1.3–10.3) | 4 (3–13) | 0.62 | 0.02 |
ICU stay, day | 7 (4.3–8) | 7 (5–7) | 7 (5.3–9.5) | 7 (5–7) | 0.42 | 0.67 |
Admission route | 0.01 | 0.85 | ||||
ICU | 0 | 3 (2.3) | 1 (11.1) | 2 (1.7) | ||
Emergency department | 6 (50.0) | 60 (46.2) | 7 (77.8) | 53 (43.8) | ||
General ward | 6 (50.0) | 67 (51.5) | 1 (11.1) | 66 (54.5) |
Values are presented as median (interquartile range) or number (%). Percentages in parentheses represent the percentage of the total patient population, except for age and MELD score, which represent the range observed in the population.
MRSA, methicillin-resistant Staphylococcus aureus; MELD, Model for End-Stage Liver Disease; ICU, intensive care unit.
Variable |
Initially colonize |
Not initially colonized |
p valuea | |||
---|---|---|---|---|---|---|
Group 1b (n = 37) | Total (n = 105) | Group 2b (n = 21) | Group 3b (n = 84) | p valueb | ||
Age, yr | 50 (43.5–56.5) | 49 (40.3–56) | 51 (39.5–55) | 49 (41–56) | 0.91 | 0.42 |
Male sex | 29 (78.4) | 64 (61.0) | 13 (61.9) | 51 (60.7) | 0.92 | 0.06 |
Underlying liver disease | 0.30 | 0.33 | ||||
Hepatitis B | 23 (62.2) | 52 (49.5) | 9 (42.9) | 43 (51.2) | ||
Hepatitis C | 2 (5.4) | 9 (8.6) | 2 (9.5) | 7 (8.3) | ||
Hepatitis B + C | 1 (2.7) | 0 | 0 | 0 | ||
Hepatitis A | 3 (8.1) | 13 (12.4) | 2 (9.5) | 11 (13.1) | ||
Cryptogenic cirrhosis | 1 (2.7) | 4 (3.8) | 1 (4.8) | 3 (3.6) | ||
Primary biliary cirrhosis | 1 (2.7) | 0 | 0 | 0 | ||
Alcoholic liver disease | 4 (10.8) | 15 (14.3) | 3 (14.3) | 12 (14.3) | ||
Others | 2 (5.4) | 12 (11.4) | 4 (19.0) | 8 (9.5) | ||
Cause of transplantation | ||||||
Decompensated liver cirrhosis | 25(67.6) | 54 (51.4) | 9 (42.9) | 45 (53.6) | 0.38 | 0.08 |
Fulminant hepatitis | 4(10.8) | 22 (21.0) | 4 (19.0) | 18 (21.4) | 0.81 | 0.17 |
Hepatocellular carcinoma | 12(32.4) | 42 (40.0) | 8 (38.1) | 34 (40.5) | 0.84 | 0.41 |
Comorbid condition | ||||||
Diabetes mellitus | 13 (35.1) | 26 (24.8) | 7 (33.3) | 19 (22.6) | 0.31 | 0.22 |
Hypertension | 3 (8.1) | 14 (13.3) | 4 (19.0) | 10 (11.9) | 0.38 | 0.40 |
Retransplantation | 1 (2.9) | 3 (2.9) | 1 (4.8) | 2 (2.4) | 0.56 | 0.99 |
Pretransplant condition | ||||||
MELD score | 22 (16–30.7) | 16 (10–29) | 14 (9.5–31) | 16 (10–27) | 0.89 | 0.02 |
Child-Pugh, class C | 23 (62.2) | 63 (60.0) | 11 (52.4) | 52 (61.9) | 0.67 | 0.81 |
Pretransplant dialysis | 7 (18.9) | 18 (17.1) | 5 (23.8) | 13 (15.5) | 0.37 | 0.81 |
Posttransplant condition | ||||||
Reoperation | 5 (13.5) | 13 (12.4) | 4 (19.0) | 9 (10.7) | 0.30 | 0.86 |
Posttransplant dialysis | 5 (13.5) | 17 (16.1) | 4 (23.5) | 13 (16.3) | 0.47 | 0.66 |
Biliary complication | 16 (43.2) | 35 (33.3) | 6 (28.6) | 29 (34.5) | 0.61 | 0.28 |
Invasive device | ||||||
Central venous catheter | 10 (27.0) | 33 (31.4) | 6 (28.6) | 27 (32.1) | 0.76 | 0.62 |
Hemodialysis catheter | 8 (21.6) | 19 (18.1) | 4 (19.0) | 15 (17.9) | 0.90 | 0.64 |
Foley catheter | 14 (37.8) | 33 (31.4) | 4 (19.0) | 29 (34.5) | 0.17 | 0.48 |
Ventilator | 0 | 4 (3.8) | 1 (4.8) | 3 (3.6) | 0.80 | 0.23 |
History of previous hospitalization | 19 (51.4) | 50 (47.6) | 11 (52.4) | 39 (46.4) | 0.63 | 0.70 |
Preoperative hospital stay, day | 11 (4–18) | 4 (2.8–11) | 4.5 (4–7.5) | 4 (2–13) | 0.55 | < 0.01 |
ICU stay, day | 6 (5–7) | 7 (5–7) | 7 (6–9) | 4 (5–7) | 0.05 | 0.57 |
Admission route | 0.78 | 0.24 | ||||
ICU | 0 | 3 (2.9) | 1 (4.8) | 2 (2.4) | ||
Emergency department | 21 (56.8) | 45 (42.9) | 8 (38.1) | 37 (44.0) | ||
General ward | 16 (43.2) | 5 (54.3) | 12 (57.1) | 45 (53.6) |
Values are presented as median (interquartile range) or number (%). Percentages in parentheses represent the percentage of the total patient population, except for age and MELD score, which represent the range observed in the population.
VRE, vancomycin-resistant enterococci; MELD, Model for End-Stage Liver Disease; ICU, intensive care unit.