Desensitization for the prevention of drug hypersensitivity reactions
Sung-Yoon Kang, Jeongmin Seo, Hye-Ryun Kang
Korean J Intern Med. 2022;37(2):261-270. Published online February 28, 2022
Drug desensitization is the temporary induction of tolerance to a sensitized drug by administering slow increments of the drug, starting from a very small amount to a full therapeutic dose. It can be used as a therapeutic strategy for patients with drug hypersensitivity when no comparable alternativ..
|
|
Hemato-oncology
Clinical significance of rituximab infusion-related reaction in diffuse large B-cell lymphoma patients receiving R-CHOP
Kyoung Min Cho, Bhumsuk Keam, Hyerim Ha, Miso Kim, Jae-Woo Jung, Woo-Jung Song, Tae Min Kim, Yoon Kyung Jeon, Hye-Ryun Kang, Dong-Wan Kim, Chul Woo Kim, Dae Seog Heo
Korean J Intern Med. 2019;34(4):885-893. Published online November 20, 2017
Background/Aims: This study was to evaluate the clinical significance of infusion-related reaction (IRR) of rituximab in diffuse large B-cell lymphoma (DLBCL) patients who received R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone) as a first-line chemotherapy.
Methods..
|
|
Allergy
Direct costs of severe cutaneous adverse reactions in a tertiary hospital in Korea
Min-Suk Yang, Ju-Young Kim, Min-Gyu Kang, Suh-Young Lee, Jae-Woo Jung, Sang-Heon Cho, Kyung-Up Min, Hye-Ryun Kang
Korean J Intern Med. 2019;34(1):195-201. Published online February 23, 2018
Background/Aims: There are only a few reports on the direct costs of severe cutaneous adverse reactions (SCARs), including drug reaction with eosinophilia and systemic symptoms (DRESS), Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN), despite the tremendous negative impact these..
|
|
Genetic markers of severe cutaneous adverse reactions
Jae-Woo Jung, Jae-Yeol Kim, In-Won Park, Byoung-Whui Choi, Hye-Ryun Kang
Korean J Intern Med. 2018;33(5):867-875. Published online June 22, 2018
Adverse drug reactions can cause considerable discomfort. They can be life-threatening in severe cases, requiring or prolonging hospitalization, impeding proper treatment, and increasing treatment costs considerably. Although the incidence of severe cutaneous adverse reactions (SCARs) is low, they c..
|
|
Clinical features and prognostic factors of Churg-Strauss syndrome
Mi-Yeong Kim, Kyoung-Hee Sohn, Woo-Jung Song, Heung-Woo Park, Sang-Heon Cho, Kyung-Up Min, Hye-Ryun Kang
Korean J Intern Med. 2014;29(1):85-95. Published online January 2, 2014
Background/Aims: Churg-Strauss syndrome (CSS) is a rare systemic necrotizing
small-vessel vasculitis, with accompanying bronchial asthma, eosinophilia, and
eosinophilic infiltration of various tissues. The purposes of our study were to
characterize the clinical features of CSS and to identify fac..
|
|
|