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Effect of the Combined Use of Tramadol and Milnacipran on Pain Threshold in an Animal Model of Fibromyalgia

Seong-Ho Kim, Junhwa Song, Hyunil Mun, Keon Uk Park

Korean J Intern Med. 2009;24(2):139-142. Published online June 8, 2009

DOI: https://doi.org/10.3904/kjim.2009.24.2.139 Crossref 23

Background/Aims

Acidic saline injections produce mechanical hyperresponsiveness in male Sprague-Dawley rats. We investigated the effect of milnacipran in conjunction with tramadol on the pain threshold in an acidic saline animal model of pain.

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