Heart failure with preserved ejection fraction: insights from recent clinical researches

Article information

Korean J Intern Med. 2020;35(4):1026-1026
Publication date (electronic) : 2020 July 1
doi : https://doi.org/10.3904/kjim.2020.104.e1
Division of Cardiology, Korea University Anam Hospital, Seoul, Korea

Diagnostic of HFA-PEFF [15]

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Table 1.

Diagnostic of HFA-PEFF [15]

HFA-PEFF score [15]
Major
Minor
Value Point Value Point
Functional Septal e’ < 7 cm/sec or lateral e’ < 10 cm/sec 2 Avergaed E/e’ 9–14 1
or or
Averaged E/e’ ≥ 15 GLS < 16%
or
TR Vmax > 2.8 m/sec (PASP > 35 mmHg)
Morphological LAVI > 34 mL/m2 2 LAVI 29–34 mL/m2 1
or or
LVMI ≥ 149/122 g/m2 (M/W) ± RWT > 0.42 LVMI ≥ 115/95 m2 (M/W)
or
RWT > 0.42
or
LV wall thickness ≥ 12 mm
Biomarker (SR) NT-proBNP > 220 pg/mL 2 NT-proBNP 125–220 pg/mL 1
or or
BNP > 80 pg/mL BNP 35–80 pg/mL
(AF) NT-proBNP > 660 pg/mL 2 NT-proBNP 365–660 pg/mL 1
or or
BNP > 240 pg/mL BNP 105–240 pg/mL

≥ 5 points: heart failure with preserved ejection fraction; 2–4 points: exercise stress test or invasive hymodynamic measurement.

HFA-PEFF, heart Failure Association-PEFF; TR, tricuspid regurgitation; PASP, pulmonary artery systolic pressure; GLS, global longitudinal strain; LAVI, left atrial volume index; LVMI, left ventricular mass index; M/W, men/women; RWT, regional wall thickness; LV, left ventricular; SR, sinus rhythm; NT-proBNP, N-terminal pro-B type natriuretic peptide; BNP, B type natriuretic peptide; AF, atrial fibrillation.