Esophageal squamous papilloma (ESP) is a rare benign epithelial lesion characterized histologically by finger-like projections of hyperplastic squamous epithelium covering a connective tissue core. Most lesions are small, solitary, and found incidentally. It is rarely difficult for an experienced endoscopist to identify ESP because of the typical warty appearance. ESP is extremely rare and has been described in fewer than 10 cases in the English-language literature. The etiology of ESP remains unclear, although roles of chronic mucosal irritation and HPV infection have been proposed. The clinical course of ESP is variable, ranging from natural regression to the development of squamous cell carcinoma. A slowly progressive course appears to be most common. Therefore, clinicians should be aware of the malignant potential of these lesions. However, there are no standard therapeutic or surveillance guidelines for esophageal papillomatosis due to the scarcity of reported cases.