Korean J Intern Med > Volume 33(5); 2018 > Article |
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Variable | Period 1 (n = 729) | Period 2 (n = 1,420) | p value |
---|---|---|---|
Age, yr | 71 (59–78) | 70 (57–78) | 0.208 |
Male sex | 451 (61.9) | 1,006 (64.2) | 0.285 |
Patients no. with stays > 48 hr | 583 (80.0) | 1,140 (72.8) | < 0.001 |
Ventilator utilization ratioa | 0.76 (0.74–0.82) | 0.75 (0.72–0.78) | 0.462 |
Central line utilization ratioa | 0.65 (0.62–0.71) | 0.63 (0.59–0.68) | 0.265 |
Length of ICU stay, day | 5 (3–10) | 4 (1–9) | < 0.001 |
Patient-days, total | 6,418 | 11,545 | NA |
No. of patients yielding CRAB isolates | 44 (6.0) | 202 (14.2) | < 0.001 |
Sites of CRAB isolationb | |||
Surveillance cultures | 18 (2.5) | 160 (11.3) | < 0.001 |
Respiratory tract | 38 (5.2) | 143 (10.1) | < 0.001 |
Blood | 6 (0.8) | 19 (1.3) | 0.400 |
Wound | 3 (0.4) | 12 (0.8) | 0.416 |
Otherc | 5 (0.7) | 5 (0.4) | 0.321 |
No. of admission prevalent cases of CRABd | 18 (2.5) | 83 (5.8) | < 0.001 |
No. of incident cases of CRABe | 26 (3.6) | 88 (6.2) | 0.011 |
No. of incident cases of CRAB including both surveillance and clinical cultures | 26 (3.6) | 119 (8.3) | < 0.001 |
Values are presented as median (interquartile range) or number (%).
ICU, intensive care unit; NA, not applicable; CRAB, carbapenem-resistant Acinetobacter baumannii.
a Device utilization ratio is calculated by dividing the number of device-days by the number of patient-days.
Variable |
Trend before INT |
Change in level after INTa |
Change in trend after INTb |
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---|---|---|---|---|---|---|
β1 (95% CI) | p value | β2 (95% CI) | p value | β3 (95% CI) | p value | |
Admission-prevalence density of CRABc | 0.175 (0.052 to 0.298) | 0.005 | 0.164 (–0.673 to 1.001) | 0.700 | –0.185 (–0.310 to –0.059) | 0.004 |
Incidence density of CRABd | 0.347 (0.175 to 0.517) | < 0.001 | 0.289 (–0.409 to 0.987) | 0.417 | –0.413 (–0.585 to –0.240) | < 0.001 |
Incidence density of CRAB including both ASC and clinical culturese | 0.347 (0.161 to 0.532) | < 0.001 | 0.513 (–0.206 to 1.232) | 0.162 | –0.406 (–0.594 to –0.219) | < 0.001 |
Incidence density of MRSAf | 0.025 (–0.043 to 0.092) | 0.472 | –0.137 (–1.023 to 0.750) | 0.763 | –0.067 (–0.150 to 0.011) | 0.091 |