Korean J Intern Med > Epub ahead of print |
|
Characteristic | Total (n = 30) | No change (n = 18) | Elevated E/e’ (n = 12) | p value |
---|---|---|---|---|
Age, yr | 49.3 ± 10.2 | 50.7 ± 9.8 | 47.1 ± 10.8 | 0.346 |
Male sex | 21 (70) | 14 (77) | 7 (58) | 0.418 |
Body mass index, kg/m2 | 25.0 ± 3.1 | 24.5 ± 3.0 | 25.8 ± 3.1 | 0.253 |
Body surface area, m2 | 1.79 ± 0.18 | 1.80 ± 0.28 | 1.78 ± 0.08 | 0.759 |
Hypertension | 28 (93) | 17 (94) | 11 (91) | 1.000 |
Diabetes mellitus | 22 (73) | 15 (83) | 7 (58) | 0.210 |
Hyperlipidemia | 10 (33) | 9 (50) | 1 (8) | 0.024a |
Smoking | 10 (33) | 5 (27) | 5 (41) | 0.461 |
Duration of PD, mon | 12.3 ± 19.7 | 12.1 ± 23.1 | 12.7 ± 9.4 | 0.950 |
Values are presented as mean ± SD or number (%).
eGFR, estimated glomerular filtration rate; PTH, parathyroid hormone; CRP, C-reactive protein; NT-proBNP, N-terminal prohormone of brain natriuretic peptide; ACEi/ARB, angiotensin converting enzyme inhibitor/aldosterone receptor antagonist; CCB, calcium channel blocker.
Values are presented as mean ± SD.
LVEDD, left ventricular end diastolic dimension; LVESD, left ventricular end systolic dimension; LVEDVI, left ventricular end diastolic volume index; LVESVI, left ventricular end systolic volume index; LVEF, left ventricular ejection fraction; LVMI, left ventricular mass index; LAVI, left atrial volume index; DT, deceleration time; RVSP, right ventricular systolic pressure; TAPSE, tricuspid annular peak systolic excursion.
Parameter | Total (n = 30) | No change (n = 18) | Elevated E/e’ (n = 12) | p value |
---|---|---|---|---|
LAVI, mL/m2 | 41 ± 16 | 40 ± 11 | 44 ± 22 | 0.041a |
E, cm/sec | 84 ± 20 | 88 ± 19 | 78 ± 21 | 0.190 |
A, cm/sec | 107 ± 19 | 117 ± 16 | 94 ± 13 | 0.001a |
E/A ratio | 0.8 ± 0.3 | 0.8 ± 0.2 | 0.9 ± 0.5 | 0.313 |
DT, ms | 168 ± 51 | 167 ± 38 | 169 ± 67 | 0.291 |
e’, cm/sec | 9.5 ± 3.3 | 10.0 ± 2.6 | 8.6 ± 4.0 | 0.921 |
E/e’ | 9.7 ± 3.4 | 9.0 ± 1.9 | 10.6 ± 4.6 | 0.291 |
Δ of E/e’, % | 0.94 ± 29.7 | –16.0 ± 11.6 | 26.4 ± 30.7 | 0.001a |
TAPSE | 2.8 ± 0.6 | 3.0 ± 0.7 | 2.5 ± 0.2 | 0.023a |
EDVI | 37.8 ± 8.2 | 38.2 ± 6.1 | 37.2 ± 10.9 | 0.769 |
ESVI | 13.7 ± 4.1 | 14.0 ± 3.7 | 13.4 ± 4.9 | 0.767 |
LVEF | 64.6 ± 5.4 | 64.5 ± 6.2 | 64.9 ± 4.4 | 0.840 |
Factor |
Univariate |
Multivariate |
||||
---|---|---|---|---|---|---|
HR | 95% CI | p value | HR | 95% CI | p value | |
Age | 0.966 | 0.896–1.041 | 0.361 | 1.074 | 0.944–1.221 | 0.279 |
Sex | 0.370 | 0.038–2.494 | 0.269 | - | - | - |
HTN | 2.961 | 0.362–24.21 | 0.311 | - | - | - |
DM | 0.850 | 0.156–4.647 | 0.851 | - | - | - |
Hemoglobin | 0.734 | 0.850–1.112 | 0.145 | - | - | - |
Uric acid | 1.681 | 0.967–2.922 | 0.066 | - | - | - |
NT-proBNP | 1.000 | 1.000–1.000 | 0.736 | - | - | - |
LVEF | 0.974 | 0.893–1.063 | 0.559 | - | - | - |
LAVI | 0.990 | 0.887–1.104 | 0.856 | - | - | - |
Baseline E/e’ | 0.823 | 0.641–1.051 | 0.118 | - | - | - |
Δ E/e’ | 1.113 | 1.043–1.189 | 0.001a | 1.135 | 1.039–1.241 | 0.005a |
Duke treadmill score | 0.950 | 0.748–1.208 | 0.678 | - | - | - |