KJIM :: Korean Journal of Internal Medicine

Emerging therapeutic landscape on delivery of oxytocin to brain for treating neurological disorders

Samarth Kumar, Neeraj Kumar Garg, Ashay Jain, Prachi Pandey, Ajay Khopade, Krutika K. Sawant

Journal of Drug Delivery Science and Technology.2024; 92: 105370. CrossRef

Inhibition of indoleamine dioxygenase leads to better control of tuberculosis adjunctive to chemotherapy

Bindu Singh, Chivonne Moodley, Dhiraj K. Singh, Ruby A. Escobedo, Riti Sharan, Garima Arora, Shashank R. Ganatra, Vinay Shivanna, Olga Gonzalez, Shannan Hall-Ursone, Edward J. Dick, Deepak Kaushal, Xavier Alvarez, Smriti Mehra

Prevalence and associated factors of diabetes mellitus among patients with tuberculosis in South Korea from 2011 to 2018: a nationwide cohort study

Dawoon Jeong, Jeongha Mok, Doosoo Jeon, Hee-Yeon Kang, Hee Jin Kim, Hee-Sun Kim, Jeong Mi Seo, Hongjo Choi, Young Ae Kang

Immune Responses in Lung Granulomas during Mtb/HIV Co-Infection: Implications for Pathogenesis and Therapy

Interactive effect of oral anti-hyperglycaemic or anti–hypertensive drugs on the inhibitory and bactericidal activity of first line anti-TB drugs against M. tuberculosis

Effect of Metformin on Plasma Exposure of Rifampicin, Isoniazid, and Pyrazinamide in Patients on Treatment for Pulmonary Tuberculosis

Agibothu Kupparam Hemanth Kumar, Abhijit Kadam, Ramesh Karunaianantham, Manoharan Tamizhselvan, Chandrasekaran Padmapriyadarsini, Anant Mohan, B. Jeyadeepa, Ammayappan Radhakrishnan, Urvashi B. Singh, Shraddha Bapat, Aarti Mane, Pradeep Kumar, Megha Mamul

Pulmonary tuberculosis and diabetes mellitus: Epidemiology, pathogenesis and therapeutic management (Review)

Randomized Trial of Metformin With Anti-Tuberculosis Drugs for Early Sputum Conversion in Adults With Pulmonary Tuberculosis

Chandrasekaran Padmapriydarsini, Megha Mamulwar, Anant Mohan, Prema Shanmugam, N S Gomathy, Aarti Mane, Urvashi B Singh, Nathella Pavankumar, Abhijeet Kadam, Hemanth Kumar, Chandra Suresh, Devaraju Reddy, Poornaganga Devi, P M Ramesh, Lakshmanan Sekar, Sh

Clinical Infectious Diseases.2022; 75(3): 425. CrossRef

Recent Advances in Host-Directed Therapies for Tuberculosis and Malaria

Kely C. Matteucci, André A. S. Correa, Diego L. Costa

Frontiers in Cellular and Infection Microbiology.2022;[Epub] CrossRef

Increased susceptibility to pneumonia due to tumour necrosis factor inhibition and prospective immune system rescue via immunotherapy

Frontiers in Cellular and Infection Microbiology.2022;[Epub] CrossRef

Metformin promotes smear conversion in tuberculosis‐diabetes comorbidity and construction of prediction models

Yili Wang, Yanbing Zhou, Liyu Chen, Yuhui Cheng, Hongli Lai, Mengyuan Lyu, Jiongjiong Zeng, Yao Zhang, Ping Feng, Binwu Ying

Journal of Clinical Laboratory Analysis.2022;[Epub] CrossRef

Effect of Oral Antidiabetic Drugs on Tuberculosis Risk and Treatment Outcomes: Systematic Review and Meta-Analysis

Edinson Dante Meregildo-Rodriguez, Martha Genara Asmat-Rubio, Petterson Zavaleta-Alaya, Gustavo Adolfo Vásquez-Tirado

Tropical Medicine and Infectious Disease.2022; 7(11): 343. CrossRef

The Changing Paradigm of Drug-Resistant Tuberculosis Treatment: Successes, Pitfalls, and Future Perspectives

Navisha Dookie, Senamile L. Ngema, Rubeshan Perumal, Nikita Naicker, Nesri Padayatchi, Kogieleum Naidoo

Clinical Microbiology Reviews.2022;[Epub] CrossRef

Host-directed therapies in pulmonary tuberculosis: Updates on anti-inflammatory drugs

Juan M. Cubillos-Angulo, Betânia M. F. Nogueira, María B. Arriaga, Beatriz Barreto-Duarte, Mariana Araújo-Pereira, Catarina D. Fernandes, Caian L. Vinhaes, Klauss Villalva-Serra, Vanessa M. Nunes, João P. Miguez-Pinto, Eduardo P. Amaral, Bruno B. Andrade

Modulating macrophage function to reinforce host innate resistance against Mycobacterium avium complex infection

Hyun-Eui Park, Wonsik Lee, Sangwon Choi, Myunghwan Jung, Min-Kyoung Shin, Sung Jae Shin

Prevalence of Pulmonary Tuberculosis in Diabetic Patients: Epidemiology, Immunological Basis, and Its Amalgamated Management

Repurposing of Metformin for the prevention and treatment of Tuberculosis

Navya Vyas, Rakhi Punchathidil, Ansuman Swain, Irfan Shakeer, Badikol Shrikar Reddy, Mohan Kamalanivas Manu, Sonal Sekhar Miraj

Brazilian Journal of Pharmaceutical Sciences.2022;[Epub] CrossRef

Impact of metformin therapy on health‐related quality of life outcomes in tuberculosis patients with diabetes mellitus in India: A prospective study

Ritu Mishra, Shri Krishan, Ali Nasir Siddiqui, Prem Kapur, Khalid Umer Khayyam, Pradeep Kumar Rai, Manju Sharma

International Journal of Clinical Practice.2021;[Epub] CrossRef

Targeting Autophagy as a Strategy for Developing New Vaccines and Host-Directed Therapeutics Against Mycobacteria

Human monocyte-derived macrophage responses to M. tuberculosis differ by the host's tuberculosis, diabetes or obesity status, and are enhanced by rapamycin

Blanca I. Restrepo, Arshad Khan, Vipul K. Singh, Erica de-Leon, Génesis P. Aguillón-Durán, Eder Ledezma-Campos, David H. Canaday, Chinnaswamy Jagannath

The Prospect of Repurposing Immunomodulatory Drugs for Adjunctive Chemotherapy against Tuberculosis: A Critical Review

Host‐directed therapy to combat mycobacterial infections*

Gül Kilinç, Anno Saris, Tom H. M. Ottenhoff, Mariëlle C. Haks

Repurposing Immunomodulatory Drugs to Combat Tuberculosis

Samreen Fatima, Ashima Bhaskar, Ved Prakash Dwivedi

Host Immune-Metabolic Adaptations Upon Mycobacterial Infections and Associated Co-Morbidities

Alba Llibre, Martin Dedicoat, Julie G. Burel, Caroline Demangel, Matthew K. O’Shea, Claudio Mauro

The cumulative dose-dependent effects of metformin on the development of tuberculosis in patients newly diagnosed with type 2 diabetes mellitus

Eunyoung Heo, Eunyoung Kim, Eun Jin Jang, Chang-Hoon Lee

Repurposing diphenylbutylpiperidine-class antipsychotic drugs for host-directed therapy of Mycobacterium tuberculosis and Salmonella enterica infections

M. T. Heemskerk, C. J. Korbee, J. J. Esselink, C. Carvalho dos Santos, S. van Veen, I. F. Gordijn, F. Vrieling, K. V. Walburg, C. G. Engele, K. Dijkman, L. Wilson, F. A. W. Verreck, T. H. M. Ottenhoff, M. C. Haks

Metformin for Cardiovascular Protection, Inflammatory Bowel Disease, Osteoporosis, Periodontitis, Polycystic Ovarian Syndrome, Neurodegeneration, Cancer, Inflammation and Senescence: What Is Next?

ACS Pharmacology & Translational Science.2021; 4(6): 1747. CrossRef

Metformin promotes Mycobacterium tuberculosis killing and increases the production of human β-defensins in lung epithelial cells and macrophages

Adrian Rodriguez-Carlos, Claudia Valdez-Miramontes, Paulina Marin-Luevano, Irma González-Curiel, Jose A. Enciso-Moreno, Bruno Rivas-Santiago

Microbes and Infection.2020; 22(3): 111. CrossRef

Impacts of metformin on tuberculosis incidence and clinical outcomes in patients with diabetes: a systematic review and meta-analysis

European Journal of Clinical Pharmacology.2020; 76(2): 149. CrossRef

Therapeutic host-directed strategies to improve outcome in tuberculosis

Medicamentos versátiles: buscando balas mágicas

Marco Antonio Yamazaki-Nakashimada, Francisco Eduardo Rivas-Larrauri, Luis Adrián Rosales-Hernández

Revista Latinoamericana de Infectología Pediátrica.2020; 33(1): 32. CrossRef

Effects of host‐directed therapies on the pathology of tuberculosis

The Journal of Pathology.2020; 250(5): 636. CrossRef

Metformin as Host-Directed Therapy for TB Treatment: Scoping Review

Immunometabolism during Mycobacterium tuberculosis Infection

Trends in Microbiology.2020; 28(10): 832. CrossRef

Potential anti-TB investigational compounds and drugs with repurposing potential in TB therapy: a conspectus

Adetomiwa A. Adeniji, Kirsten E. Knoll, Du Toit Loots

Applied Microbiology and Biotechnology.2020; 104(13): 5633. CrossRef

Of tuberculosis and non-tuberculous mycobacterial infections – a comparative analysis of epidemiology, diagnosis and treatment

Radha Gopalaswamy, Sivakumar Shanmugam, Rajesh Mondal, Selvakumar Subbian

Journal of Biomedical Science.2020;[Epub] CrossRef

Metformin enhances anti-mycobacterial responses by educating CD8+ T-cell immunometabolic circuits

Julia Böhme, Nuria Martinez, Shamin Li, Andrea Lee, Mardiana Marzuki, Anteneh Mehari Tizazu, David Ackart, Jessica Haugen Frenkel, Alexandra Todd, Ekta Lachmandas, Josephine Lum, Foo Shihui, Tze Pin Ng, Bernett Lee, Anis Larbi, Mihai G. Netea, Randall Bas

Metformin and Rifampicin combination augments active to latent tuberculosis conversion: A computational study

Deepak Yadav, Sumanpreet Kaur, Dibyajyoti Banerjee, Rajasri Bhattacharyya

Biotechnology and Applied Biochemistry.2020;[Epub] CrossRef

The Effect of Metformin in Experimentally Induced Animal Models of Epileptic Seizure

Ebrahim M. Yimer, Awol Surur, Dawit Zewdu Wondafrash, Abadi Kahsu Gebre

Metformin as a host-directed therapeutic in tuberculosis: Is there a promise?

Wing Wai Yew, Kwok Chiu Chang, Denise P. Chan, Ying Zhang

Improving treatment outcomes for MDR-TB — Novel host-directed therapies and personalised medicine of the future

Martin Rao, Giuseppe Ippolito, Sayoki Mfinanga, Francine Ntoumi, Dorothy Yeboah-Manu, Cris Vilaplana, Alimuddin Zumla, Markus Maeurer

International Journal of Infectious Diseases.2019; 80: S62. CrossRef

Reduced prevalence of latent tuberculosis infection in diabetes patients using metformin and statins

Matthew J. Magee, Argita D. Salindri, Hardy Kornfeld, Amit Singhal

European Respiratory Journal.2019; 53(3): 1801695. CrossRef

Metformin Alters Human Host Responses to Mycobacterium tuberculosis in Healthy Subjects

Ekta Lachmandas, Clare Eckold, Julia Böhme, Valerie A C M Koeken, Mardiana Binte Marzuki, Bastiaan Blok, Rob J W Arts, Jinmiao Chen, Karen W W Teng, Jacqueline Ratter, Elise J Smolders, Corina Van den Heuvel, Rinke Stienstra, Hazel M Dockrell, Evan Newell

The Journal of Infectious Diseases.2019; 220(1): 139. CrossRef

Metformin in tuberculosis: beyond control of hyperglycemia

William Oglesby, Ali M. Kara, Hector Granados, Jorge L. Cervantes

Analytical Exploration of Potential Pathways by which Diabetes Mellitus Impacts Tuberculosis Epidemiology

Susanne F. Awad, Soha R. Dargham, Ryosuke Omori, Fiona Pearson, Julia A. Critchley, Laith J. Abu-Raddad

Pulmonary tuberculous cavities in diabetic patients

Li-Kuo Huang, Liang-De Jiang, Yi-Chun Lai, Mei-Han Wu, Shi-Chuan Chang

Journal of the Chinese Medical Association.2019; 82(8): 628. CrossRef

Changes in Host Response to Mycobacterium tuberculosis Infection Associated With Type 2 Diabetes: Beyond Hyperglycemia

Cristian Alfredo Segura-Cerda, Wendy López-Romero, Mario Alberto Flores-Valdez

Frontiers in Cellular and Infection Microbiology.2019;[Epub] CrossRef

Impact of metformin on the risk and treatment outcomes of tuberculosis in diabetics: a systematic review

Xinyu Yu, Ling Li, Liangtao Xia, Xin Feng, Fan Chen, Shiyi Cao, Xiang Wei

Impact of metformin use among tuberculosis close contacts with diabetes mellitus in a nationwide cohort study

Ming-Chia Lee, Chih-Hsin Lee, Meng-Rui Lee, Jann-Yuan Wang, Shih-Ming Chen

Metformin reduces the relapse rate of tuberculosis patients with diabetes mellitus: experiences from 3-year follow-up

Y. Ma, Y. Pang, W. Shu, Y.-H. Liu, Q.-P. Ge, J. Du, L. Li, W.-W. Gao

European Journal of Clinical Microbiology & Infectious Diseases.2018; 37(7): 1259. CrossRef

Effect of Diabetes Mellitus on the Pharmacokinetics and Pharmacodynamics of Tuberculosis Treatment

Omamah Alfarisi, Vidya Mave, Sanjay Gaikwad, Tushar Sahasrabudhe, Geetha Ramachandran, Hemanth Kumar, Nikhil Gupte, Vandana Kulkarni, Sona Deshmukh, Sachin Atre, Swapnil Raskar, Rahul Lokhande, Madhusudan Barthwal, Arjun Kakrani, Sandy Chon, Amita Gupta,

Antimicrobial Agents and Chemotherapy.2018;[Epub] CrossRef