KJIM :: Korean Journal of Internal Medicine

Ginsenoside CK improves skeletal muscle insulin resistance by activating DRP1/PINK1-mediated mitophagy

Weili Li, Haiyang Li, Lujuan Zheng, Jing Xia, Xiaoxuan Yang, Shuhan Men, Ye Yuan, Yuying Fan

Recent Advances in Yeast Recombinant Biosynthesis of the Triterpenoid Protopanaxadiol and Glycosylated Derivatives Thereof

Journal of Agricultural and Food Chemistry.2023; 71(5): 2197. CrossRef

Hypolipidemic effect and molecular mechanism of ginsenosides: a review based on oxidative stress

Wei Jin, Chunrun Li, Shihui Yang, Shiyi Song, Weiwei Hou, Yang Song, Quanyu Du

Frontiers in Pharmacology.2023;[Epub] CrossRef

A novel dammarane triterpenoid alleviates atherosclerosis by activating the LXRα pathway

Yan Huang, Xiaodong Ran, Hongmei Liu, Mingming Luo, Yiyu Qin, Jinqiong Yan, Xiaohui Li, Yi Jia

Ginsenoside compound K ameliorates palmitate-induced atrophy in C2C12 myotubes via promyogenic effects and AMPK/autophagy-mediated suppression of endoplasmic reticulum stress

Tae Jin Kim, Do Hyeon Pyun, Myeong Jun Kim, Ji Hoon Jeong, A.M. Abd El-Aty, Tae Woo Jung

Journal of Ginseng Research.2022; 46(3): 444. CrossRef

Upregulation of adiponectin by Ginsenoside Rb1 contributes to amelioration of hepatic steatosis induced by high fat diet

Yaru Li, Shuchen Zhang, Ziwei Zhu, Ruonan Zhou, Pingyuan Xu, Lingyan Zhou, Yue Kan, Jiao Li, Juan Zhao, Penghua Fang, Xizhong Yu, Wenbin Shang

Journal of Ginseng Research.2022; 46(4): 561. CrossRef

AMPK signaling in diabetes mellitus, insulin resistance and diabetic complications: A pre-clinical and clinical investigation

Maliheh Entezari, Danial Hashemi, Afshin Taheriazam, Amirhossein Zabolian, Shima Mohammadi, Farima Fakhri, Mehrdad Hashemi, Kiavash Hushmandi, Milad Ashrafizadeh, Ali Zarrabi, Yavuz Nuri Ertas, Sepideh Mirzaei, Saeed Samarghandian

Biomedicine & Pharmacotherapy.2022; 146: 112563. CrossRef

Compound K attenuates hyperglycemia by enhancing glucagon-like peptide-1 secretion through activating TGR5 via the remodeling of gut microbiota and bile acid metabolism

Fengyuan Tian, Shuo Huang, Wangda Xu, Lan Chen, Jianming Su, Haixiang Ni, Xiaohong Feng, Jie Chen, Xi Wang, Qi Huang

Journal of Ginseng Research.2022; 46(6): 780. CrossRef

Ginsenoside compound K increases glucagon-like peptide-1 release and L-cell abundance in db/db mice through TGR5/YAP signaling

Fengyuan Tian, Wangda Xu, Lan Chen, Tianxi Chen, Xiaohong Feng, Jie Chen, Danning Wei, Qi Huang

International Immunopharmacology.2022; 113: 109405. CrossRef

Ginsenoside Compound K Through TGR5/YAP Signal To Increase Glucagon-Like Peptide-1 Release and L-Cell Number in db/db Mice

Fengyuan Tian, Wangda Xu, Lan Chen, Tianxi Chen, Xiaohong Feng, Jie Chen, Danning Wei, Qi Huang

SSRN Electronic Journal .2022;[Epub] CrossRef

Ginsenosides Improve Nonalcoholic Fatty Liver Disease via Integrated Regulation of Gut Microbiota, Inflammation and Energy Homeostasis

Wenyi Liang, Kun Zhou, Ping Jian, Zihao Chang, Qiunan Zhang, Yuqi Liu, Shuiming Xiao, Lanzhen Zhang

Frontiers in Pharmacology.2021;[Epub] CrossRef

Ginsenoside Compound K Promotes Intestinal Peristalsis and the Pharmacokinetic of Metabolite 20(S)-Protopanaxadiol in Relation to Diarrhea

Lulu Chen, Luping Zhou, Xiangchang Zeng, Jianwei Liao, Guoping Yang, Zhirong Tan, Dongsheng Ouyang, Zhenyu Li, Tingting Hong

Journal of Nanomaterials.2021; 2021: 1. CrossRef

Allopurinol ameliorates high fructose diet induced hepatic steatosis in diabetic rats through modulation of lipid metabolism, inflammation, and ER stress pathway

In-Jin Cho, Da-Hee Oh, Jin Yoo, You-Cheol Hwang, Kyu Jeung Ahn, Ho-Yeon Chung, Soung Won Jeong, Ju-Young Moon, Sang-Ho Lee, Sung-Jig Lim, In-Kyung Jeong

Ginsenoside F2 Suppresses Adipogenesis in 3T3-L1 Cells and Obesity in Mice via the AMPK Pathway

Jing Zhou, Ji Zhang, Jiayi Li, Yiqiu Guan, Ting Shen, Fu Li, Xueqin Li, Xiaojun Yang, Weicheng Hu

Journal of Agricultural and Food Chemistry.2021; 69(32): 9299. CrossRef

Hypoglycemic and Hypolipidemic Effects of Malonyl Ginsenosides from American Ginseng (Panax quinquefolius L.) on Type 2 Diabetic Mice

Zhi Liu, Chun-Yuan Qu, Jia-Xin Li, Yan-Fang Wang, Wei Li, Chong-Zhi Wang, Dong-Sheng Wang, Jia Song, Guang-Zhi Sun, Chun-Su Yuan

Ginsenoside compound K alleviates sodium valproate-induced hepatotoxicity in rats via antioxidant effect, regulation of peroxisome pathway and iron homeostasis

Luping Zhou, Lulu Chen, Xiangchang Zeng, Jianwei Liao, Dongsheng Ouyang

Toxicology and Applied Pharmacology.2020; 386: 114829. CrossRef

Dammarane-type leads panaxadiol and protopanaxadiol for drug discovery: Biological activity and structural modification

Mingying Wang, Haonan Li, Weiwei Liu, Hao Cao, Xu Hu, Xiang Gao, Fanxing Xu, Zhanlin Li, Huiming Hua, Dahong Li

European Journal of Medicinal Chemistry.2020; 189: 112087. CrossRef

Effects of compound K, a metabolite of ginsenosides, on memory and cognitive dysfunction in db/db mice involve the inhibition of ER stress and the NLRP3 inflammasome pathway

Chu-Wen Li, Min-Zhen Deng, Zhi-Jie Gao, Yuan-Ye Dang, Guo-Dong Zheng, Xiu-Juan Yang, Ying-Xin Chao, Ye-Feng Cai, Xiao-Li Wu

Ginsenoside Compound K: Insights into Recent Studies on Pharmacokinetics and Health-Promoting Activities

Lactobacillus fermentum KP-3-fermented ginseng ameliorates alcohol-induced liver disease in C57BL/6N mice through the AMPK and MAPK pathways

Ying You, Yan-long Liu, Zhi-Yi Ai, Yu-Shan Wang, Jun-Mei Liu, Chun-Hong Piao, Yu-Hua Wang

Food & Function.2020; 11(11): 9801. CrossRef

Ginsenosides for the treatment of metabolic syndrome and cardiovascular diseases: Pharmacology and mechanisms

Wenxiang Fan, Yongliang Huang, Hui Zheng, Shuiqin Li, Zhuohong Li, Li Yuan, Xi Cheng, Chengshi He, Jianfeng Sun

Biomedicine & Pharmacotherapy.2020; 132: 110915. CrossRef

Improving hepatic mitochondrial biogenesis as a postulated mechanism for the antidiabetic effect ofSpirulina platensisin comparison with metformin

Ghaleb A. Oriquat, Mennatallah A. Ali, Shimaa A. Mahmoud, Rania M.H.M. Eid, Rania Hassan, Maher A. Kamel

Applied Physiology, Nutrition, and Metabolism.2019; 44(4): 357. CrossRef

Therapeutic Potential of Ginsenosides as an Adjuvant Treatment for Diabetes

Litao Bai, Jialiang Gao, Fan Wei, Jing Zhao, Danwei Wang, Junping Wei

Frontiers in Pharmacology.2018;[Epub] CrossRef

Protective effect of triterpenes against diabetes-induced β-cell damage: An overview of in vitro and in vivo studies

Sihle E. Mabhida, Phiwayinkosi V. Dludla, Rabia Johnson, Musawenkosi Ndlovu, Johan Louw, Andy R. Opoku, Rebamang A. Mosa

Pharmacological Research.2018; 137: 179. CrossRef

New Insights into the Mechanisms of Chinese Herbal Products on Diabetes: A Focus on the “Bacteria-Mucosal Immunity-Inflammation-Diabetes” Axis

Zezheng Gao, Qingwei Li, Xuemin Wu, Xuemin Zhao, Linhua Zhao, Xiaolin Tong

Journal of Immunology Research.2017; 2017: 1. CrossRef