EGFR and KRAS Mutations in Patients With Adenocarcinoma of the Lung
Tae Won Jang, Chul Ho Oak, Hee Kyung Chang, Soon Jung Suo, Mann Hong Jung
Korean J Intern Med. 2009;24(1):48-54.   Published online 2009 Mar 6     DOI:
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Yanqing Chen, Yang Yang, Longbai Ma, Huiyuan Zhu, Tienan Feng, Sen Jiang, Youyong Wei, Tingting Wang, Xiwen Sun
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Hope S. Rugo, Jack A. Di Palma, Debu Tripathy, Richard Bryce, Susan Moran, Elizabeth Olek, Linda Bosserman
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Zsolt Mervai, Krisztina Egedi, Ilona Kovalszky, Kornélia Baghy
BMC Cancer.2018;[Epub]     CrossRef
Does the efficacy of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor differ according to the type of EGFR mutation in non-small cell lung cancer?
Yong Won Choi, Jin-Hyuk Choi
The Korean Journal of Internal Medicine.2017; 32(3): 422.     CrossRef
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Min Ah Kim, Jin-Hyoung Kang, In-Ho Kim, Tae-Jung Kim, Seung Joon Kim, Sook Whan Sung, Sol Mi Huo
The Korean Journal of Medicine.2016; 90(1): 72.     CrossRef
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Eun Young Kim, Eun Na Cho, Heae Surng Park, Arum Kim, Ji Young Hong, Seri Lim, Jong Pil Youn, Seung Yong Hwang, Yoon Soo Chang
BMC Cancer.2016;[Epub]     CrossRef
CUSTOM-SEQ: a prototype for oncology rapid learning in a comprehensive EHR environment
Jeremy L Warner, Lucy Wang, William Pao, Jeffrey A Sosman, Ravi V Atreya, Pam Carney, Mia A Levy
Journal of the American Medical Informatics Associ.2016; 23(4): 692.     CrossRef
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American Journal of Clinical Oncology.2016; : 1.     CrossRef
Bronchial-pulmonary adenocarcinoma subtyping relates with different molecular pathways
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Acta Pharmacologica Sinica.2015; 36(3): 291.     CrossRef
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Analysis of an EGFR mutation by PNA clamping method in lung carcinoid tumors
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Kosin Medical Journal.2015; 30(2): 141.     CrossRef
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Eun Young Kim, Arum Kim, Se Kyu Kim, Hyung Jung Kim, Joon Chang, Chul Min Ahn, Jae Seok Lee, Hyo Sup Shim, Yoon Soo Chang
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Correlation Between EGFR Mutation Status and Computed Tomography Features in Patients With Advanced Pulmonary Adenocarcinoma
Jui-Sheng Hsu, Ming-Shyan Huang, Chiao-Yun Chen, Gin-Chung Liu, Ta-Chih Liu, Inn-Wen Chong, Shah-Hwa Chou, Chih-Jen Yang
Journal of Thoracic Imaging.2014; 29(6): 357.     CrossRef
WITHDRAWN: Bronchial-pulmonary adenocarcinoma subtyping relates with different molecular pathways
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Epidermal growth factor receptor and KRAS mutations in lung adenocarcinoma: A retrospective study of the Lebanese population
Oncology Reports.2014; 32(5): 2223.     CrossRef
EGFR Mutations in Surgically Resected Fresh Specimens from 697 Consecutive Chinese Patients with Non-Small Cell Lung Cancer and Their Relationships with Clinical Features
Yuanyang Lai, Zhipei Zhang, Jianzhong Li, Dong Sun, Yong'an Zhou, Tao Jiang, Yong Han, Lijun Huang, Yifang Zhu, Xiaofei Li, Xiaolong Yan
International Journal of Molecular Sciences.2013; 14(12): 24549.     CrossRef
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Nicolas Girard
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Diagnostic Molecular Pathology.2013; 22(1): 22.     CrossRef
Can mutations of EGFR and KRAS in serum be predictive and prognostic markers in patients with advanced non-small cell lung cancer (NSCLC)?
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Medical Oncology.2013;[Epub]     CrossRef
CDKN2A/p16 Inactivation Mechanisms and Their Relationship to Smoke Exposure and Molecular Features in Non–Small-Cell Lung Cancer
Kit W. Tam, Wei Zhang, Junichi Soh, Victor Stastny, Min Chen, Han Sun, Kelsie Thu, Jonathan J. Rios, Chenchen Yang, Crystal N. Marconett, Suhaida. A. Selamat, Ite A. Laird-Offringa, Ayumu Taguchi, Samir Hanash, David Shames, Xiaotu Ma, Michael Q. Zhang, W
Journal of Thoracic Oncology.2013; 8(11): 1378.     CrossRef
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EGFR and KRAS mutation analyses from specimens obtained by bronchoscopy and EBUS-TBNA
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Clinical Sarcoma Research.2013; 3(1): 3.     CrossRef
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Pathology & Oncology Research.2012; 18(4): 783.     CrossRef
Gefitinib in Selected Patients with Pre-Treated Non-Small-Cell Lung Cancer: Results from a Phase IV, Multicenter, Non-Randomized Study (SELINE)
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EGFR mutations in non-small-cell lung cancer among smokers and non-smokers: A meta-analysis
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Environmental and Molecular Mutagenesis.2012; 53(1): 78.     CrossRef
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Cancer Investigation.2012; 30(5): 433.     CrossRef
Driver mutations as predictive biomarkers in lung cancer
Nicolas Girard
Current Respiratory Care Reports.2012; 1(1): 21.     CrossRef
Establishment and characterization of primary lung cancer cell lines from Chinese population
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Acta Pharmacologica Sinica.2011; 32(3): 385.     CrossRef
EGFR and KRAS mutations in Chinese patients with adenosquamous carcinoma of the lung
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Lung Cancer.2011; 74(3): 396.     CrossRef
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Epidermal Growth Factor Receptor Mutations as a Prognostic Factor in Korean Patients with Advanced Lung Adenocarcinoma Who Had Not Been Treated with Received Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors
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Chemotherapy.2011; 57(2): 108.     CrossRef
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Journal of the Korean Society of Coloproctology.2011; 27(3): 127.     CrossRef
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Ronald van Eijk, Jappe Licht, Melanie Schrumpf, Mehrdad Talebian Yazdi, Dina Ruano, Giusi I. Forte, Petra M. Nederlof, Maud Veselic, Klaus F. Rabe, Jouke T. Annema, Vincent Smit, Hans Morreau, Tom van Wezel, Ralf Krahe
PLoS ONE.2011; 6(3): e17791.     CrossRef
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Clinical Oncology and Cancer Research.2010; 7(2): 97.     CrossRef
Chromosomal imbalances in lung adenocarcinomas with or without mutations in the epidermal growth factor receptor gene
Yao FONG, Yue-Shan LIN, Chiou-Ping LIOU, Chien-Fen LI, Ching-Cherng TZENG
Respirology.2010; 15(4): 700.     CrossRef
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Cancer Investigation.2010; 28(4): 413.     CrossRef
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Asfar S Azmi, Philip A Philip, Syed F Zafar, Fazlul H Sarkar, Ramzi M Mohammad
Expert Opinion on Therapeutic Targets.2010; 14(6): 611.     CrossRef
Chemotherapy for lung cancer: the state of the art in 2009
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