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ORIGINAL ARTICLE 2018 February 23
Duodenal Niemann-Pick C1-like 1 expression was negatively correlated with liver X receptor expression in nonalcoholic fatty liver disease
1. Niemann-Pick C1-like 1 (NPC1L1) is expressed in the small intestine and is a promising target in nonalcoholic fatty liver disease (NAFLD) treatment. It is known that liver X receptor (LXR) was associated hepatic fat homeostasis.
2. There are no human studies on expression of NPC1L1 in patients with NAFLD.
3. Duodenal NPC1L1 expression was decreased in NAFLD and was negatively correlated with LXR expression in peripheral mononuclear cells.
Current status of endoscopic submucosal dissection for early gastric cancer in Korea: role and benefits
1. Endoscopic submucosal dissection (ESD) was performed in 67.4% of cases in tertiary care hospital in Korea.
2. Total median medical costs of ESD was 1,300 US dollars in Korea.
3. Clinical status of ESD was not changed by the year and among the types of hospitals in Korea.
Daclatasvir and asunaprevir combination therapy for patients with chronic hepatitis C virus genotype 1b infection in real world
1. Daclatasvir and asunaprevir combination therapy showed high rates of rapid virologic response, end-of-treatment response, and sustained virologic response at 12 weeks after completion of treatment (SVR12) when used to treat patients with chronic hepatitis C virus genotype 1b infection in real world.
2. Daclatasvir and asunaprevir combination therapy was well tolerated without serious adverse events.
Volume34 No. 4
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Treadmill exercise-induced E/e’ elevation as a predictor of cardiovascular event in end-stage renal disease on peritoneal dialysis ( 30,384 times )
Received April 13, 2016  Accepted May 13, 2016  Published online November 11, 2016
DOI: https://doi.org/10.3904/kjim.2016.254            Cited By 2   [Epub ahead of print]
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