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ORIGINAL ARTICLE 2017 September 13
Comparison of liquid-based cytology (CellPrepPlus) and conventional smears in pancreaticobiliary disease
1. Liquid-based cytology is widely used for preparing gynecological and nongynecological cytology specimens.
2. Compared to the conventional smear, liquid-based cytology possesses sound sample quality, easiness owing to automation, shortened analysis time, fewer cellular overlaps and dryness, and fewer impacts from blood and inflammation.
3. Liquid-based cytology showed a lower diagnostic rate in pancreatic endoscopic ultrasound-guided fine needle aspiration cytology and biliary brush cytology compared to conventional smears.
ORIGINAL ARTICLE 2017 October 24
Characteristics of Helicobacter pylori-seropositive subjects according to the stool antigen test findings: a prospective study
1. Most (> 80%) of the Helicobacter pylori-seropositive subjects showed positive stool test findings.
2. The presence of H. pylori antigen in stool was independently related to a higher serum pepsinogen (PG) I level and a lower serum PG I/II ratio, which denote an active current H. pylori infection with increased gastric secreting ability.
3. Seropositive subjects with increased gastric secreting ability tend to have H. pylori in their fecal material as reflected by a positive stool H. pylori antigen test finding.
ORIGINAL ARTICLE 2018 January 17
Disparity in Crohn’s disease activity between home and clinics is associated with unscheduled hospital visits due to disease flares
1. A self-reporting symptom monitoring using a smart phone can find that a third of patients with Crohn’s disease have a different activity between the home and routine outpatient clinic visits, which may not have been detected using the traditional Crohn’s Disease Activity Index.
2. This disparity of disease activity is associated with the poor clinical outcomes such as bowel resection surgery and unscheduled hospital visits due to disease flares.
ORIGINAL ARTICLE 2017 December 18
Body fluid status assessment by bio-impedance analysis in patients presenting to the emergency department with dyspnea
1. In acute heart failure (AHF) patients, the ratio of extracellular water divided by total body water (ECW/TBW) is significantly increased in all segments, especially in lower extremities.
2. Among the body compartments, ECW/TBW of lower extremities has the most accurate predictive power for AHF. With the reference value of 0.412, the sensitivity and specificity are 0.780 and 0.960, respectively.
3. In multivariate analysis, increased level of ECW/TBW > 0.412 from lower extremities is an independent diagnostic marker for AHF diagnosis.
ORIGINAL ARTICLE 2017 November 7
Early experience and favorable clinical outcomes of everolimus-eluting bioresorbable scaffolds for coronary artery disease in Korea
1. Although data from randomized trials raise concerns about stent thrombosis (ST) after bioresorbable vascular scaffold (BVS) implantation, in this first-experience report of BVS in Korea, using a real-world all-comer registry, the use of Absorb BVS demonstrated excellent procedural feasibility and favorable clinical outcomes without ST at early-term follow-up.
2. Strategy of meticulous lesion preparation and intracoronary image-guided post-balloon dilation, complying with PSP implant technique (Preparing the lesion adequately before scaf­fold placement; Sizing appropriately; Post-dilatation with the use of a non-compliant balloon) may be associated with these encouraging early results.
3. Aggressive antiplatelet therapy including cilostazol add-on dual antiplatelet therapy might contribute to preventing ST following BVS implantation, which should be investigated in further studies.
ORIGINAL ARTICLE 2018 March 16
The effect of metformin on culture conversion in tuberculosis patients with diabetes mellitus
1. Concurrent diabetes mellitus (DM) and tuberculosis (TB) is associated with a higher prevalence of TB, more frequent treatment failures and relapses.
2. Macrophage’s autophagy activation mechanism called host-directed therapy by metformin is proposed.
3. Metformin can be an effective adjunctive anti-TB agent in DM patients with a high bacillary burden.
Volume33 No. 5
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