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ORIGINAL ARTICLE 2017 December 14
Effect of Helicobacter pylori eradication on the regression of gastric polyps in National Cancer Screening Program
1. Helicobacter pylori eradication induced the disappearance of hyperplastic polyp in National Cancer Screening Cohort. 2. Gastric polyp size was inversely associated with the disappearance of hyperplastic polyp. 3. Age and sex had no association with regression of hyperplastic polyps.
ORIGINAL ARTICLE 2017 January 11
Prognostic value of total triiodothyronine and free thyroxine levels for the heart failure in patients with acute myocardial infarction
1. Lower levels of total triiodothyronine (T3) were well correlated with 1-year major adverse cardiovascular and cerebrovascular events in percutaneous coronary intervention-treated acute myocardial infarction patients, especially hear failure (HF) requiring re-hospitalization. 2. The T3/free thyroxine levels can be an additional marker to predict HF.
ORIGINAL ARTICLE 2017 October 19
Anti-platelet effects of epigallocatechin-3-gallate in addition to the concomitant aspirin, clopidogrel or ticagrelor treatment
1. Epigallocatechin-3-gallate (EGCG) significantly reduced adenosine diphosphate and collagen-induced platelet aggregation in dose-dependent manner. 2. EGCG also suppressed shear stress-induced platelet adhesion, but had no effect on P-selectin and PAC-1 expressions. 3. EGCG did not suppress platelet aggregation any further in subjects already took anti-platelet agents. It implied no increased bleeding risk by EGCG.
ORIGINAL ARTICLE 2017 December 15
Combination of carboplatin and intermittent normobaric hyperoxia synergistically suppresses benzo[a]pyrene-induced lung cancer
1. Intermittent normobaric hyperoxia with carboplatin displays a synergistic tumoricidal effect in a mouse lung cancer model. 2. Addition of hyperoxia to chemotherapy enhanced oxidative stress, which is considered to induce cell death mainly via apoptosis. 3. Intermittent normobaric hyperoxia may be a useful adjuvant therapy for lung cancer.
ORIGINAL ARTICLE 2017 February 8
Reference intervals of thyroid hormones during pregnancy in Korea, an iodine-replete area
1. Korean pregnant women have wider ranges of thyroid hormone reference intervals and pregnancy outcomes did not vary in mothers with subtle changes in thyroid function. 2. These findings will reduce the number of pregnant women who may be classified as having subclinical hypothyroidism and are subjected to unnecessary levothyroxine treatment.
ORIGINAL ARTICLE 2017 March 13
Comparison of tolvaptan treatment between patients with the SIADH and congestive heart failure: a single-center experience
1. The early response to tolvaptan treatment was better in patients with syndrome of inappropriate antidiuretic hormone secretion (SIADH) than in those with congestive heart failure (CHF). 2. The mean maintenance dose was larger and the total duration of tolvaptan use was slightly longer in the CHF than SIADH group. 3. The tolvaptan treatment strategy should be differed between patients with SIADH and those with CHF.
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