Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. The only curative treatment modalities for HCC are surgery, percutaneous ablation, and liver transplantation. Unfortunately, the majority of patients have unresectable disease at diagnosis. Therefore, effective treatment opt..
Dyspepsia refers to group of commonly occurring upper gastrointestinal symptoms. The majority of patients with dyspepsia suffer from functional (nonulcer) dyspepsia. Although there is a lack of epidemiological data from population-based or patient cohort studies in Korea, the current understanding o..
Background/Aims: The purpose of this study was to investigate the expression of urokinase-type plasminogen activator (uPA), uPA receptor (uPAR), and plasminogen activator inhibitor (PAI)-1 on podocytes in immunoglobulin A (IgA) glomerulonephritis (GN).
Methods: Renal biopsy specimens from 52 IgA G..
Background/Aims: Although indoor air pollution is a well-known risk factor for tuberculosis (TB), the possible link between outdoor air pollution and TB development has not been examined fully. We assessed the impact of outdoor air pollution on TB development in the Seoul metropolitan area, South Ko..
Background/Aims: Nonsteroidal anti-inflammatory drugs relieve osteoarthritis (OA) symptoms but cause adverse effects. D-002, a mixture of beeswax alcohols, is effective against experimental OA. A pilot study found that D-002 (50 mg/day) for 8 weeks improves OA symptoms. The aim of this study was to ..
Background/Aims: With the increasing incidence of cardiovascular disease, angiocardiography using contrast-enhancing media has become an essential diagnostic and therapeutic tool, despite the risk of contrast-medium-induced acute kidney injury (CIAKI). CIAKI may be exacerbated by renin-angiotensin-s..
Yun-Kyeong Cho, Chang-Wook Nam, Hyoung-Seob Park, Hyuck-Jun Yoon, Hyungseop Kim, Seung-Ho Hur, Yoon-Nyun Kim, Jang-Hoon Lee, Dong-Heon Yang, Bong-Ryeol Lee, Byung-Chun Jung, Woong Kim, Jong-Seon Park, Jin-Bae Lee, Kee-Sik Kim, Kwon-Bae Kim
Korean J Intern Med. 2014;29(2):210-216. Published online February 27, 2014
Background/Aims: Combination single-pill therapy can improve cost-effectiveness in a typical medical therapy. However, there is a little evidence about the efficacy and tolerability of combination single-pill antiplatelet therapy after percutaneous coronary intervention (PCI) with drug-eluting stent..
Background/Aims: Primary aldosteronism (PA) is now widely recognized to have a higher prevalence than was once thought. In view of its increasing prevalence, we compared chronological changes in clinical manifestations of PA according to different times of diagnosis.
Methods: In total, 85 patients d..
Background/Aims: The aim of this study is to measure the difference of ionized calcium between heparinized whole blood and serum.
Methods: We recruited 107 maintenance hemodialysis (HD) patients from our hospital HD unit. The clinical and laboratory data included ionized calcium in serum and in wh..
Dermatomyositis is an idiopathic inflammatory myopathy with typical cutaneous manifestations. It has been proposed that dermatomyositis may be caused by autoimmune responses to viral infections. Previous studies have shown an association between dermatomyositis and malignant tumors such as ovarian c..
Myocarditis often occurs due to viral infections and postviral immune-mediated responses. Hypersensitivity myocarditis is a rare form of myocarditis. Numerous drugs can induce myocarditis, which is typically reversible after withdrawal of the causative agent. Here, we report a case of hypersensitivi..
The diameter and collapsibility of the inferior vena cava (IVC) should be interpreted in consideration with other clinical and echocardiographic parameters before drawing definitive diagnostic conclusions. We report a case of a 46-year-old female with isolated IVC dilation and diminished inspiratory..
Ifosfamide-induced Fanconi syndrome is a rare complication that typically occurs in young patients due to a cumulative dose of ifosfamide > 40–60 g/m2, a reduction in kidney mass, or concurrent cisplatin treatment. It is usually characterized by severe and fatal progression accompanied by type II ..
Ji Hyeon Baek, Yu Bin Seo, Won Suk Choi, Sae Yoon Kee, Hye Won Jeong, Hee Young Lee, Byung Wook Eun, Eun Ju Choo, Jacob Lee, Sung Ran Kim, Young Keun Kim, Joon Young Song, Seong-Heon Wie, Jin-Soo Lee, Hee Jin Cheong, Woo Joo Kim, Transgovernmental Enterprise for Pandemic Influenza in Korea
Korean J Intern Med. 2014;29(2):265-280. Published online February 27, 2014