Angiogenesis is a complex biological phenomenon that forms new blood vessels
from the pre-existing vasculature. Aberrant angiogenesis has been implicated in
a variety of diseases such as cancer, atherosclerosis, arthritis, obesity, pulmonary
hypertension, diabetic retinopathy, and age-related mac..
S100A8 and S100A9 are major leukocyte proteins, known as damage-associated
molecular patterns, found at high concentrations in the synovial fluid of patients
with rheumatoid arthritis (RA). A heterodimeric complex of S100A8/A9 is secreted
by activated leukocytes and binds to Toll-like receptor 4,..
Jung Hee Kim, Hyun Wook Baik, Yeong Sook Yoon, Hyo Jee Joung, Ju Sang Park, Sang Jong Park, Eun Jeong Jang, Sang Woon Park, Sang Jung Kim, Mi Jeoung Kim, Dong Ok Jeon, Hyo Jin Cho, Sang Jin Lee, Sung Gyu Im, Sun Kyung Jang
Korean J Intern Med. 2014;29(1):31-39. Published online January 2, 2014
Background/Aims: Oxidative stress increases the risk of cardiovascular complications
of metabolic syndrome (MetS). This study was conducted to examine the
difference in antioxidant capacity according to the presence of MetS, and to characterize
the association between antioxidant capacity and Me..
Background/Aims: Sunitinib is an oral multitargeted tyrosine kinase inhibitor
used mainly for the treatment of metastatic renal cell carcinoma. The renal adverse
effects (RAEs) of sunitinib have not been investigated. The aim of this study
was to determine the incidence and risk factors of RAEs (..
Background/Aims: To enable appropriate antimicrobial treatment for community-
onset infections in emergency departments (EDs), data are needed on the
resistance profiles of Escherichia coli and Klebsiella pneumoniae, which are the main
pathogens of community-onset bacteremia.
Methods: Records we..
Sang Jun Suh, Hyung Joon Yim, Eileen L. Yoon, Beom Jae Lee, Jong Jin Hyun, Sung Woo Jung, Ja Seol Koo, Ji Hoon Kim, Kyung Jin Kim, Rok Son Choung, Yeon Seok Seo, Jong Eun Yeon, Soon Ho Um, Kwan Soo Byun, Sang Woo Lee, Jai Hyun Choi, Ho Sang Ryu
Korean J Intern Med. 2014;29(1):57-65. Published online January 2, 2014
Background/Aims: In patients with liver cirrhosis, drugs acting on the central
nervous system can lead to hepatic encephalopathy and the effects may be prolonged.
Recently, misuse of propofol has been reported and the associated risk of
death have become an issue. Propofol is commonly used during..
Background/Aims: While drug-eluting stents (DESs) have shown favorable outcomes
in ST‑segment elevation myocardial infarction (STEMI) compared to bare
metal stents (BMSs), there are concerns about the risk of stent thrombosis (ST)
with DESs. Because intravascular ultrasound (IVUS) guidance may ..
Background/Aims: We investigated the agreement between the QuantiFERON-
TB Gold (QFT‑Gold) test and the tuberculin skin test (TST) in the diagnosis
of latent tuberculosis infection in patients with rheumatoid arthritis (RA), compared
with healthy controls, in Korea.
Methods: We recruited 64 pa..
Background/Aims: Churg-Strauss syndrome (CSS) is a rare systemic necrotizing
small-vessel vasculitis, with accompanying bronchial asthma, eosinophilia, and
eosinophilic infiltration of various tissues. The purposes of our study were to
characterize the clinical features of CSS and to identify fac..
Primary duodenal adenocarcinoma is a rare malignant neoplasm accounting for
0.3% of all gastrointestinal tract carcinomas. We herein present one case of duodenal
adenocarcinoma after duodenal neuroendocrine carcinoma. Poorly differentiated
duodenal neuroendocrine carcinoma with liver metastasis (..
A 71-year-old male patient was readmitted to our hospital 1 month after discharge
because of relapse of abdominal pain. He had been diagnosed with hepatocellular
carcinoma (HCC) 1 year prior and had undergone repeated transcatheter arterial
chemoembolization and radiotherapy. During the last hosp..
Spontaneous coronary artery dissection is a rare cause of acute coronary syndrome
and sudden cardiac death. The incidence, causes, pathogenesis, and treatment
have not been defined clearly, but spontaneous coronary artery dissection
should be considered in young patients without major cardiovascu..
Hypothermia, defined as an unintentional decline in the core body temperature
to below 35°C, is a life-threatening condition. Patients with malnutrition and
diabetes mellitus as well as those of advanced age are at high risk for accidental
hypothermia. Due to the high mortality rates of acciden..
Won Suk Choi, Ji Hyeon Baek, Yu Bin Seo, Sae Yoon Kee, Hye Won Jeong, Hee Young Lee, Byung Wook Eun, Eun Ju Choo, Jacob Lee, Young Keun Kim, Joon Young Song, Seong-Heon Wie, Jin Soo Lee, Hee Jin Cheong, Woo Joo Kim; Transgovernmental Enterprise for Pandemic Influenza in Korea
Korean J Intern Med. 2014;29(1):132-147. Published online January 2, 2014