| Reviews |
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Cardiology
Antiangiogenesis therapy: an update after the first
decade
Sandro De Falco
Korean J Intern Med. 2014;29(1):1-11. Published online January 2, 2014
Angiogenesis is a complex biological phenomenon that forms new blood vessels
from the pre-existing vasculature. Aberrant angiogenesis has been implicated in
a variety of diseases such as cancer, atherosclerosis, arthritis, obesity, pulmonary
hypertension, diabetic retinopathy, and age-related mac..
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Rheumatology
S100A8/A9 as a biomarker for synovial inflammation
and joint damage in patients with rheumatoid
arthritis
Kwi Young Kang, Jung-Won Woo, Sung-Hwan Park
Korean J Intern Med. 2014;29(1):12-19. Published online January 2, 2014
S100A8 and S100A9 are major leukocyte proteins, known as damage-associated
molecular patterns, found at high concentrations in the synovial fluid of patients
with rheumatoid arthritis (RA). A heterodimeric complex of S100A8/A9 is secreted
by activated leukocytes and binds to Toll-like receptor 4,..
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| Editorials |
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Oxidative stress, point-of-care test, and metabolic
syndrome
Ji Sun Nam, Chul Woo Ahn
Korean J Intern Med. 2014;29(1):20-22. Published online January 2, 2014
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Risks associated with sunitinib use and monitoring
to improve patient outcomes
Bum Soon Choi
Korean J Intern Med. 2014;29(1):23-26. Published online January 2, 2014
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| Original Articles |
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Endocrinology-metabolism
Measurement of antioxidant capacity using the biological antioxidant potential test and its role as a predictive marker of metabolic syndrome
Jung Hee Kim, Hyun Wook Baik, Yeong Sook Yoon, Hyo Jee Joung, Ju Sang Park, Sang Jong Park, Eun Jeong Jang, Sang Woon Park, Sang Jung Kim, Mi Jeoung Kim, Dong Ok Jeon, Hyo Jin Cho, Sang Jin Lee, Sung Gyu Im, Sun Kyung Jang
Korean J Intern Med. 2014;29(1):31-39. Published online January 2, 2014
Background/Aims: Oxidative stress increases the risk of cardiovascular complications
of metabolic syndrome (MetS). This study was conducted to examine the
difference in antioxidant capacity according to the presence of MetS, and to characterize
the association between antioxidant capacity and Me..
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Nephrology
Renal adverse effects of sunitinib and its clinical significance: a single-center experience in Korea
Seon Ha Baek, Hyunsuk Kim, Jeonghwan Lee, Dong Ki Kim, Kook-Hwan Oh, Yon Su Kim, Jin Suk Han, Tae Min Kim, Se-Hoon Lee, Kwon-Wook Joo
Korean J Intern Med. 2014;29(1):40-48. Published online January 2, 2014
Background/Aims: Sunitinib is an oral multitargeted tyrosine kinase inhibitor
used mainly for the treatment of metastatic renal cell carcinoma. The renal adverse
effects (RAEs) of sunitinib have not been investigated. The aim of this study
was to determine the incidence and risk factors of RAEs (..
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Infectious diseases
Third-generation cephalosporin resistance of community-onset Escherichia coli and Klebsiella pneumoniae bacteremia in a secondary hospital
Shinwon Lee, Seung Woo Han, Kun Woo Kim, Do young Song, Ki Tae Kwon
Korean J Intern Med. 2014;29(1):49-56. Published online January 2, 2014
Background/Aims: To enable appropriate antimicrobial treatment for community-
onset infections in emergency departments (EDs), data are needed on the
resistance profiles of Escherichia coli and Klebsiella pneumoniae, which are the main
pathogens of community-onset bacteremia.
Methods: Records we..
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Gastroenterology
Is propofol safe when administered to cirrhotic patients during sedative endoscopy?
Sang Jun Suh, Hyung Joon Yim, Eileen L. Yoon, Beom Jae Lee, Jong Jin Hyun, Sung Woo Jung, Ja Seol Koo, Ji Hoon Kim, Kyung Jin Kim, Rok Son Choung, Yeon Seok Seo, Jong Eun Yeon, Soon Ho Um, Kwan Soo Byun, Sang Woo Lee, Jai Hyun Choi, Ho Sang Ryu
Korean J Intern Med. 2014;29(1):57-65. Published online January 2, 2014
Background/Aims: In patients with liver cirrhosis, drugs acting on the central
nervous system can lead to hepatic encephalopathy and the effects may be prolonged.
Recently, misuse of propofol has been reported and the associated risk of
death have become an issue. Propofol is commonly used during..
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Cardiology
Long-term outcomes of intravascular
ultrasound-guided implantation of bare metal
stents versus drug-eluting stents in primary
percutaneous coronary intervention
Yun-Kyeong Cho, Seung-Ho Hur, Nam-Hee Park, Sang-Woong Choi, Ji-Hyun Sohn, Hyun-Ok Cho, Hyoung-Seob Park, Hyuck-Jun Yoon, Hyungseop Kim, Chang-Wook Nam, Yoon-Nyun Kim, Kwon-Bae Kim
Korean J Intern Med. 2014;29(1):66-75. Published online January 2, 2014
Background/Aims: While drug-eluting stents (DESs) have shown favorable outcomes
in ST‑segment elevation myocardial infarction (STEMI) compared to bare
metal stents (BMSs), there are concerns about the risk of stent thrombosis (ST)
with DESs. Because intravascular ultrasound (IVUS) guidance may ..
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Rheumatology
Poor agreement between QuantiFERON-TB
Gold test and tuberculin skin test results for the
diagnosis of latent tuberculosis infection in
rheumatoid arthritis patients and healthy controls
Joo-Hyun Lee, Hae Sook Sohn, Jin Ho Chun, Hyoun-Ah Kim, Chang Hee Suh, Yun Woo Lee, Bo Young Yoon
Korean J Intern Med. 2014;29(1):76-84. Published online January 2, 2014
Background/Aims: We investigated the agreement between the QuantiFERON-
TB Gold (QFT‑Gold) test and the tuberculin skin test (TST) in the diagnosis
of latent tuberculosis infection in patients with rheumatoid arthritis (RA), compared
with healthy controls, in Korea.
Methods: We recruited 64 pa..
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Allergy
Clinical features and prognostic factors of Churg-Strauss syndrome
Mi-Yeong Kim, Kyoung-Hee Sohn, Woo-Jung Song, Heung-Woo Park, Sang-Heon Cho, Kyung-Up Min, Hye-Ryun Kang
Korean J Intern Med. 2014;29(1):85-95. Published online January 2, 2014
Background/Aims: Churg-Strauss syndrome (CSS) is a rare systemic necrotizing
small-vessel vasculitis, with accompanying bronchial asthma, eosinophilia, and
eosinophilic infiltration of various tissues. The purposes of our study were to
characterize the clinical features of CSS and to identify fac..
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| Case Reports |
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Duodenal adenocarcinoma following a
neuroendocrine tumor in the duodenum
Bun Kim, Ji Hye Huh, Youngsook Kim, Moon Jae Chung, Jeong Youp Park, Si Young Song, Seung Woo Park
Korean J Intern Med. 2014;29(1):96-100. Published online January 2, 2014
Primary duodenal adenocarcinoma is a rare malignant neoplasm accounting for
0.3% of all gastrointestinal tract carcinomas. We herein present one case of duodenal
adenocarcinoma after duodenal neuroendocrine carcinoma. Poorly differentiated
duodenal neuroendocrine carcinoma with liver metastasis (..
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Hepatoduodenal fistula formation following
transcatheter arterial chemoembolization and
radiotherapy for hepatocellular carcinoma:
treatment with endoscopic Histoacryl injection
Jaryong Jeon, Joonseong Ahn, Hongseok Yoo, Taek Kyu Park, Dongmo Je, Hyemin Jeong, Kwang Hyuck Lee
Korean J Intern Med. 2014;29(1):101-105. Published online January 2, 2014
A 71-year-old male patient was readmitted to our hospital 1 month after discharge
because of relapse of abdominal pain. He had been diagnosed with hepatocellular
carcinoma (HCC) 1 year prior and had undergone repeated transcatheter arterial
chemoembolization and radiotherapy. During the last hosp..
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Spontaneous coronary artery dissection by
intravascular ultrasound in a patient with
myocardial infarction
Ji Hun Jang, Dae Hyeok Kim, Dong Hyuk Yang, Seong Il Woo, Jun Kwan, Keum Soo Park, Sung-Hee Shin
Korean J Intern Med. 2014;29(1):106-110. Published online January 2, 2014
Spontaneous coronary artery dissection is a rare cause of acute coronary syndrome
and sudden cardiac death. The incidence, causes, pathogenesis, and treatment
have not been defined clearly, but spontaneous coronary artery dissection
should be considered in young patients without major cardiovascu..
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Hypothermia-induced acute kidney injury in an
elderly patient
Hyun Ju Yoon, Mun Chul Kim, Jae Woo Park, Min A Yang, Cheon Beom Lee, In O Sun, Kwang Young Lee
Korean J Intern Med. 2014;29(1):111-115. Published online January 2, 2014
Hypothermia, defined as an unintentional decline in the core body temperature
to below 35°C, is a life-threatening condition. Patients with malnutrition and
diabetes mellitus as well as those of advanced age are at high risk for accidental
hypothermia. Due to the high mortality rates of acciden..
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| Letters to the editor |
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Diabetic ketoacidosis as a presenting symptom of
complicated pancreatic cancer
Kyung Ae Lee, Kyung Taek Park, Woong Ji Kim, Tae Sun Park, Hong Sun Baek, Heung Yong Jin
Korean J Intern Med. 2014;29(1):116-119. Published online January 2, 2014
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Neuropathic truncal pain in patients with type 2
diabetes mellitus relieved by topical cream and
nerve block
Sun Hee Kim, Cho-Ok Baek, Kyung Ae Lee, Heung Yong Jin, Hong Sun Baek, Tae Sun Park
Korean J Intern Med. 2014;29(1):120-122. Published online January 2, 2014
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Successful treatment of myelodysplastic
syndrome and Behcet colitis after allogeneic
hematopoietic stem cell transplantation
Min-Ha Kook, Ho-Young Yhim, Na-Ri Lee, Eun-Kee Song, Hee Sun Kim, Chang-Yeol Yim, Jae-Yong Kwak
Korean J Intern Med. 2014;29(1):123-125. Published online January 2, 2014
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Eosinophilic organ infiltration without
eosinophilia or direct parasite infection
Il Young Jang, Young-Joo Yang, Hyung Jin Cho, Yunsik Choi, Eun-Hye Shin, Dong-Uk Kang, Tae-Bum Kim
Korean J Intern Med. 2014;29(1):126-129. Published online January 2, 2014
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| Images of interest |
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Acupuncture needle: an obscure cause of anal pain
Tae Hee Lee, Joon Seong Lee
Korean J Intern Med. 2014;29(1):130-130. Published online January 2, 2014
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Cervical spine fracture in advanced ankylosing
spondylitis
Jennifer Lee, Sung-Hwan Park, Kyung-Su Park
Korean J Intern Med. 2014;29(1):131-131. Published online January 2, 2014
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| Guideline |
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Severe influenza treatment guideline
Won Suk Choi, Ji Hyeon Baek, Yu Bin Seo, Sae Yoon Kee, Hye Won Jeong, Hee Young Lee, Byung Wook Eun, Eun Ju Choo, Jacob Lee, Young Keun Kim, Joon Young Song, Seong-Heon Wie, Jin Soo Lee, Hee Jin Cheong, Woo Joo Kim; Transgovernmental Enterprise for Pandemic Influenza in Korea
Korean J Intern Med. 2014;29(1):132-147. Published online January 2, 2014
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