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Allergy
The burden of symptomatic patients with chronic spontaneous urticaria: a real-world study in Korea
Young-Min Ye, Young-Il Koh, Jeong-Hee Choi, Mi-Ae Kim, Jung-Won Park, Tae-Bum Kim, Young-Hee Nam, Yoon-Seok Chang, Hae-Sim Park
Korean J Intern Med. 2022;37(5):1050-1060. Published online September 1, 2022
Background/Aims: Chronic spontaneous urticaria (CSU) poses a considerable burden both on the quality of life (QoL) of individual patients and on healthcare systems. Real‑world data evaluating the disease burden of CSU are limited in this country. This study evaluated the disease burden and healthc..
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Serum potential biomarkers according to sputum inflammatory cell profiles in adult asthmatics
Gyu-Young Hur, Young-Min Ye, Eunmi Yang, Hae-Sim Park
Korean J Intern Med. 2020;35(4):988-997. Published online November 15, 2019
Background/Aims: Asthma is not a single disease but, rather, a heterogeneous inf lammatory disorder with various pathogenic mechanisms. We analyzed the associations between the cellular profile of sputum and the serum levels of inflammatory mediators/cytokines in a cohort of adult asthmatics.
Metho..
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Disease-specific impairment of the quality of life in adult patients with chronic spontaneous urticaria
Won-Sun Choi, Eun-Soo Lim, Ga-Young Ban, Ji-Hye Kim, Yoo-Seob Shin, Hae-Sim Park, Young-Min Ye
Korean J Intern Med. 2018;33(1):185-192. Published online June 1, 2016
Background/Aims: Chronic urticaria (CU) is a common skin disorder characterized by wheals and pruritus lasting more than 6 weeks. Due to its long duration and changeable symptoms, the quality of life (QOL) of patients with CU can be impaired substantially. We evaluated the CU-QOL, a previously valid..
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Association of autophagy related gene polymorphisms with neutrophilic airway inflammation in adult asthma
Duy Le Pham, Seung-Hyun Kim, Purevsuren Losol, Eun-Mi Yang, Yoo Seob Shin, Young-Min Ye, Hae-Sim Park
Korean J Intern Med. 2016;31(2):375-385. Published online December 23, 2015
Background/Aims: Role of autophagy in neutrophil function and the association of autophagy and autophagy related (ATG) gene polymorphisms with asthma susceptibility were suggested. In this study, we investigated the genetic association of ATG5 and ATG7 polymorphisms with asthma risk, s..
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Clinical features of elderly chronic urticaria
Ga-Young Ban, Mi-Yea Kim, Hye-Soo Yoo, Dong-Ho Nahm, Young-Min Ye, Yoo-Seob Shin, Hae-Sim Park
Korean J Intern Med. 2014;29(6):800-806. Published online October 31, 2014
Background/Aims: Chronic urticaria (CU) is defined as itchy wheals lasting 6 weeks or more. As the aged population increases worldwide, it is essential to identify the specific features of this disease in the elderly population.
Methods: We investigated the prevalence and clinical features of CU in..
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