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Rheumatology
Distribution of serum uric acid levels and prevalence of hyper- and hypouricemia in a Korean general population of 172,970
Bon San Koo, Hye-Jin Jeong, Chang-Nam Son, Sang-Hyon Kim, Hyun Jung Kim, Gheun-Ho Kim, Jae-Bum Jun
Korean J Intern Med. 2021;36(Suppl 1):S264-S272. Published online November 24, 2020
Background/Aims: We investigated the distribution of serum uric acid (SUA) levels and estimated the prevalence of hyperuricemia and hypouricemia in the Korean population.
Methods: This cross-sectional study used data from the Korean Genome and Epidemiology Study and included 172,970 participants (5..
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Renal effects of uric acid: hyperuricemia and hypouricemia
Jung Hwan Park, Yong-Il Jo, Jong-Ho Lee
Korean J Intern Med. 2020;35(6):1291-1304. Published online September 9, 2020
The prevalence of chronic kidney disease (CKD) is increasing worldwide. Although hyperuricemia has been associated with CKD in many studies, it remains controversial whether this is the cause or the result of decreased renal function. Recent observational studies of healthy populations and patients ..
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Rheumatology
Clinical features and recurrent attack in gout patients according to serum urate levels during an acute attack
Jung Sun Lee, Oh Chan Kwon, Ji Seon Oh, Yong-Gil Kim, Chang-Keun Lee, Bin Yoo, Seokchan Hong
Korean J Intern Med. 2020;35(1):240-248. Published online January 28, 2019
Background/Aims: A substantial portion of gout patients have normal serum urate levels during an acute attack but data on the clinical characteristics and risk of recurrence compared with hyperuricemic patients are limited. Methods: In this retrospective cohort study, clinical features of normourice..
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Gastroenterology
Clinical implication of serum uric acid level in pegylated interferon and ribavirin combination therapy for chronic hepatitis C infection
In Soo Oh, Joung Won Won, Hyung Joon Kim, Hyun Woong Lee
Korean J Intern Med. 2017;32(6):1010-1017. Published online August 11, 2017
Background/Aims: Combined treatment of pegylated interferon-α (PEG-IFN) and ribavirin (RBV) has long been accepted as the standard treatment for chronic hepatitis C virus (HCV) infection. Many predictive factors for treatment response have been identified. The aim of this study was to evaluate the..
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Rheumatology
Prevalence and possible causes of hypouricemia at a tertiary care hospital
Chang-Nam Son, Ji-Min Kim, Sang-Hyon Kim, Soo-Kyung Cho, Chan-Bum Choi, Yoon-Kyoung Sung, Tae-Hwan Kim, Sang-Cheol Bae, Dae-Hyun Yoo, Jae-Bum Jun
Korean J Intern Med. 2016;31(5):971-976. Published online March 9, 2016
Background/Aims: We aimed to investigate the prevalence and possible causes of hypouricemia in the Korean population and to compare our findings with published results of other populations.
Methods: We examined the serum uric acid levels of 30,757 subjects who had their uric acid values measured at..
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Clinical factors and treatment outcomes associated with failure in the detection of urate crystal in patients with acute gouty arthritis
Jun Won Park, Dong Jin Ko, Jong Jin Yoo, Sung Hae Chang, Hyon Joung Cho, Eun Ha Kang, Jin Kyun Park, Yeong Wook Song, Yun Jong Lee
Korean J Intern Med. 2014;29(3):361-369. Published online April 29, 2014
Background/Aims: To investigate the rate of detection of monosodium urate (MSU) crystals in the synovial fluid (SF) of patients with acute gouty arthritis and factors associated with false-negative results.
Methods: A total of 179 patients with acute gouty arthritis who had undergo..
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Combination of Uric Acid and NT-ProBNP: A More Useful Prognostic Marker for Short-Term Clinical Outcomes in Patients with Acute Heart Failure
Hyoung-Seob Park, Hyungseop Kim, Ji-Hyun Sohn, Hong-Won Shin, Yun-Kyeong Cho, Hyuck-Jun Yoon, Chang-Wook Nam, Seung-Ho Hur, Yoon-Nyun Kim, Kwon-Bae Kim, Hee-Joon Park
Korean J Intern Med. 2010;25(3):253-259. Published online August 31, 2010
Background/AimsIn patients with heart failure (HF), N-terminal prohormone brain natriuretic peptide (NT-ProBNP) is a standard prognostic indicator. In addition, uric acid (UA) was recently established as a prognostic marker for poor outcome in chronic HF. The aim of this stud..
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Clinical Value of Serum Uric Acid in Patients with Suspected Coronary Artery Disease
Hong Euy Lim, Seong Hwan Kim, Eung Ju Kim, Jin Won Kim, Seung Woon Rha, Hong Seog Seo, Chang Gyu Park
Korean J Intern Med. 2010;25(1):21-26. Published online February 26, 2010
Background/AimsAlthough increased serum uric acid (SUA) concentrations are commonly encountered in patients with risk factors for coronary artery disease (CAD), the clinical value of SUA has not been established. MethodsThe study group comprised..
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