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Gastroenterology
The effect of Hericium erinaceum on the prevention of chemically induced experimental colitis in rats
Ali Durmus, Ilgim Durmus, Omer Bender, Oguzhan Karatepe
Korean J Intern Med. 2021;36(Suppl 1):S44-S52. Published online June 19, 2020
Background/Aims: The aim of this study is to investigate the effects of the Hericium erinaceum on an experimental colitis model.
Methods: Twenty-four Wistar albino were included in this study. Rats were divided into three groups. Group 1 (n = 8) was sham group. Group 2 is the group of chemic..
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Helicobacter pylori-derived outer membrane vesicles stimulate interleukin 8 secretion through nuclear factor kappa B activation
Mun Sun Choi, Eun Young Ze, Jae Yong Park, Tae-Seop Shin, Jae Gyu Kim
Korean J Intern Med. 2021;36(4):854-867. Published online November 27, 2020
Background/Aims: Bacteria-derived outer membrane vesicles (OMVs) are commonly associated with various biological activities and functions. Helicobacter pylori-derived OMVs are thought to contribute to pathogenesis. This study aimed to investigate the effects of H. pylori-derived OMVs.
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Cardiology
Effects of cigarette smoking on blood lipids in Korean men: Cardiovascular and Metabolic Diseases Etiology Research Center cohort
Soo Kyoung Kim, Hyeon Chang Kim, Jee-Seon Shim, Dae Jung Kim
Korean J Intern Med. 2020;35(2):369-382. Published online December 18, 2019
Background/Aims: Cigarette smoking and abnormal blood lipids are major risk factors for cardiovascular disease. The results of previous studies on the relationship between cigarette smoking and dyslipidemia are controversial. In the present study, we investigated the independent association between ..
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Gastroenterology
Decreased S100B expression in chronic liver diseases
Su Jung Baik, Tae Hun Kim, Kwon Yoo, Il Hwan Moon, Ju Young Choi, Kyu Won Chung, Dong Eun Song
Korean J Intern Med. 2017;32(2):269-276. Published online June 3, 2016
Background/Aims: Hepatic innervation in liver diseases is not fully understood. We here evaluated S100B expression as a marker of hepatic nerves in patients with various chronic liver diseases, topographically and semi-quantitatively.
Methods: Liver specimens were obtained from 70 subjects (three c..
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Feasibility of α-fetoprotein as a diagnostic tool for hepatocellular carcinoma in Korea
Dae Geon Ahn, Hyung Joon Kim, Hyun Kang, Hyun Woong Lee, Si Hyun Bae, Joon Hyoek Lee, Yong Han Paik, June Sung Lee
Korean J Intern Med. 2016;31(1):46-53. Published online December 28, 2015
Background/Aims: The aim of this study was to evaluate the feasibility of α-fetoprotein (AFP) as a diagnostic tool for hepatocellular carcinoma (HCC) in Korean patients.
Methods: We retrospectively reviewed the medical records of HCC and cirrhosis patients at three hospitals. For each HCC patient..
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Rheumatology
Predictive factors of radiographic progression in ankylosing spondylitis
Hyungjin Kim, Jaejoon Lee, Joong Kyong Ahn, Jiwon Hwang, Eun-Jung Park, Hyemin Jeong, Hoon-Suk Cha, Eun-Mi Koh
Korean J Intern Med. 2015;30(3):391-397. Published online April 29, 2015
Background/Aims: The course of ankylosing spondylitis (AS) is rather variable, and the factors that predict radiographic progression remain largely obscure. In this study, we tried to determine the clinical factors and laboratory measures that are useful in predicting the radiographic progression of..
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Gestational hyperlipidemia and acute pancreatitis with underlying partial lipoprotein lipase deficiency and apolipoprotein E3/E2 genotype
Dong Hee Han, In Ho Moh, Doo-Man Kim, Sung Hee Ihm, Moon-Gi Choi, Hyung Joon Yoo, Eun-Gyoung Hong
Korean J Intern Med. 2013;28(5):609-613. Published online August 14, 2013
We report the case of a patient who experienced extreme recurrent gestational hyperlipidemia. She was diagnosed with partial lipoprotein lipase (LPL) deficiency but without an associated LPL gene mutation in the presence of the apolipoprotein E3/2 genotype. This is the first reported case of extr..
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Effects of the Transition from Premenopause to Postmenopause on Lipids and Lipoproteins: Quantification and Related Parameters
Eun Jeung Cho, Yun Joo Min, Min Seok Oh, Jee Eun Kwon, Jeung Eun Kim, Wang-Soo Lee, Kwang Je Lee, Sang-Wook Kim, Tae Ho Kim, Myung-A Kim, Chee Jeong Kim, Wang Seong Ryu
Korean J Intern Med. 2011;26(1):47-53. Published online March 2, 2011
Background/AimsThe aim of this study was to quantitatively measure changes in lipids and lipoproteins during perimenopause and to identify variables related to these changes. MethodsAmong women who had three regular health evaluations over a spa..
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Diet and Airway Obstruction: A Cross Sectional Study from the Second Korean National Health and Nutrition Examination Survey
Jin Hwa Lee, Yun Su Sim, Gee Young Suh, Jeong-Seon Ryu, Dong Ho Shin, Kyung Haeng Koh, Yeon Jae Kim, Wan Park, Hyoung Kyu Yoon, Man Jae Lee, Jung Hyun Chang,
Korean J Intern Med. 2010;25(2):132-139. Published online June 1, 2010
Background/AimsSeveral dietary factors, such as antioxidant vitamins, have potential roles in the development of obstructive lung diseases. However, the results of studies on the relationships between dietary factors and obstructive lung diseases are inconsistent. The aim of t..
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Gastric Yolk Sac Tumor: A Case Report and Review of the Literature
Yeon Soo Kim, Seok Hyun Kim, Jae Koo Seong, Byung Seok Lee, Hyun Yong Jeong, Kyu Sang Song
Korean J Intern Med. 2009;24(2):143-146. Published online June 8, 2009
Gastric yolk sac tumors are extremely rare and their prognosis is poor; most patients have widespread metastases at the time of diagnosis. The treatment of gastric yolk sac tumors consists of aggressive chemotherapy combined with radiotherapy and surgery. Here, we first report a case of gastric y..
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Overweight and Effect of Hormone Replacement Therapy on Lipid Profiles in Postmenopausal Women
Hong Sook Ko, Chee Jeong Kim, Wang Seong Ryu
Korean J Intern Med. 2005;20(1):33-39. Published online March 31, 2005
BackgroundMany experimental and observational studies have suggested that hormone replacement therapy (HRT) in postmenopausal women is cardioprotective. However, the results of randomized controlled trials have been discouraging. We attempted to evaluate the influence of overw..
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