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Atorvastatin inhibits osteoclast differentiation by suppressing NF-κB and MAPK signaling during IL-1β-induced osteoclastogenesis
Won-Seok Lee, Eun-Gyeong Lee, Myung-Soon Sung, Yun-Jung Choi, Wan-Hee Yoo
Korean J Intern Med.
2018;33(2):397-406. Published online March 28, 2017
Background/Aims: To define the effect of statins on interleukin 1β (IL-1β)-induced osteoclastogenesis and elucidate the underlying mechanisms. Methods: Bone marrow cells were obtained from 5-week-old male ICR (Institute for Cancer Research) mice, and they were cultured to differentiate them into ..
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