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Nephrology
Association between the progression of immunoglobulin A nephropathy and a controlled status of hypertension in the first year after diagnosis
Tae Ryom Oh, Hong Sang Choi, Se Won Oh, Jieun Oh, Dong Won Lee, Chang Seong Kim, Seong Kwon Ma, Soo Wan Kim, Eun Hui Bae; on behalf of the Korean GlomeruloNEphritis sTudy (KoGNET) Group
Korean J Intern Med. 2022;37(1):146-153. Published online April 8, 2021
Background/Aims: Hypertension is considered a risk factor in immunoglobulin A nephropathy (IgAN). However, after IgAN diagnosis, the relationship between early blood pressure control and renal prognosis remains unclear. This study aimed to analyze the association between the prognosis of IgAN patients and ..
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Reduction in proteinuria after immunosuppressive therapy and long-term kidney outcomes in patients with immunoglobulin A nephropathy
Shin Chan Kang, Hyung Woo Kim, Tae Ik Chang, Ea Wha Kang, Beom Jin Lim, Jung Tak Park, Tae-Hyun Yoo, Hyeon Joo Jeong, Shin-Wook Kang, Seung Hyeok Han
Korean J Intern Med. 2021;36(5):1169-1180. Published online February 10, 2021
Background/Aims: Despite controversy regarding the benefits of immunosuppressive therapy in immunoglobulin A nephropathy (IgAN), clinical outcomes may vary depending on the patient’s responsiveness to this therapy. This study evaluated long-term kidney outcomes according to the extent of proteinur..
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Allergy
Association between primary immunodeficiency and asthma exacerbation in adult asthmatics
So-Hee Lee, Ga-Young Ban, Su-Chin Kim, Chang-Gyu Chung, Hyun-Young Lee, Ji-Ho Lee, Hae-Sim Park
Korean J Intern Med. 2020;35(2):449-456. Published online June 14, 2019
Background/Aims: Primary immunodef iciency (PID) is a serious comorbid condition in adult asthmatics that have frequent exacerbations, which requires monthly replacement of intravenous immunoglobulin (IVIG). However, the prevalence and clinical significance of PID in adult asthmatics in Korea have n..
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Hemato-oncology
Methylprednisolone versus intravenous immune globulin as an initial therapy in adult primary immune thrombocytopenia
Chul Hee Kim, Yoon Seok Choi, Ji Young Moon, Duck Yong Kim, So Yeon Lee, Hyo Jin Lee, Hwan Jung Yun, Samyong Kim, Deog Yeon Jo, Ik Chan Song
Korean J Intern Med. 2019;34(2):383-389. Published online November 27, 2017
Background/Aims: Few studies have addressed whether there are differences in clinical efficacy between intravenous methylprednisolone (methyl-Pd) and intravenous immunoglobulin (IVIg) use.
Methods: We retrospectively compared platelet responses and toxicities associated with these two treatments in..
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Gastroenterology
Immunoglobulin G4-related sclerosing cholangitis
George Goodchild, Stephen P. Pereira, George Webster
Korean J Intern Med. 2018;33(5):841-850. Published online July 27, 2018
Immunoglobulin G4-related disease (IgG4-RD) is a systemic fibroinflammatory condition of which IgG4-related sclerosing cholangitis (IgG4-SC) is the biliary manifestation. In this review, we provide an overview of IgG4-RD, with a focus on the biliary manifestations. In particular, we describe the imp..
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Allergy
Disease-specific impairment of the quality of life in adult patients with chronic spontaneous urticaria
Won-Sun Choi, Eun-Soo Lim, Ga-Young Ban, Ji-Hye Kim, Yoo-Seob Shin, Hae-Sim Park, Young-Min Ye
Korean J Intern Med. 2018;33(1):185-192. Published online June 1, 2016
Background/Aims: Chronic urticaria (CU) is a common skin disorder characterized by wheals and pruritus lasting more than 6 weeks. Due to its long duration and changeable symptoms, the quality of life (QOL) of patients with CU can be impaired substantially. We evaluated the CU-QOL, a previously valid..
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Solitary immunoglobulin G4-related inflammatory pseudotumor in the abdomen wall
Yunsuek Kim, Hae Kyung Lee, Gyuhwan Hwang, In Ho Choi, Hyun-Sook Kim
Korean J Intern Med. 2017;32(5):933-935. Published online March 12, 2016
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Allergy
Relationship between serum IgA level and allergy/asthma
Woo-Jin Kim, Inseon S. Choi, Chang Seong Kim, Jeong-Hyeon Lee, Hyeon-Wook Kang
Korean J Intern Med. 2017;32(1):137-145. Published online September 2, 2016
Background/Aims: Mucosal immunoglobulin A (IgA) may prevent the entrance of allergens. This study examined the relationship between serum IgA levels (within the normal range) and sensitization to house dust mites (HDM) or airway hyper-responsiveness (AHR). Methods: The clinical records of 1,136 adul..
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Painful immunoglobulin G4-related thyroiditis treated by total thyroidectomy
Ihn Suk Lee, Jung Uee Lee, Kwan-Ju Lee, Yi Sun Jang, Jong Min Lee, Hye Soo Kim
Korean J Intern Med. 2016;31(2):399-402. Published online February 26, 2016
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Diagnostic Value of a Chimeric TSH Receptor (Mc4)-Based Bioassay for Graves' Disease
Ji In Lee, Hye Won Jang, Soo Kyoung Kim, Joon Young Choi, Ji Young Kim, Kyu Yeon Hur, Jae Hyeon Kim, Yong-Ki Min, Jae Hoon Chung, Sun Wook Kim
Korean J Intern Med. 2011;26(2):179-186. Published online June 1, 2011
Background/AimsGraves' disease (GD) is caused by thyroid-stimulating hormone receptor (TSHR) and thyroid-stimulating immunoglobulin (TSI). We used a recently introduced, technically enhanced TSI bioassay to assess its diagnostic value and determine the cut-off in patients in h..
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High-dose Immunoglobulin Infusion for Thrombotic Thrombocytopenic Purpura Refractory to Plasma Exchange and Steroid Therapy
Seh Jong Park, Seok Jin Kim, Hee Yun Seo, Moon Ju Jang, Doyeun Oh, Byung Soo Kim, Jun Suk Kim
Korean J Intern Med. 2008;23(3):161-164. Published online September 20, 2008
The outcomes of the treatment of thrombotic thrombocytopenic purpura (TTP) have been shown to be improved by the administration of plasma exchange. However, treatment options are currently limited for cases refractory to plasma exchange. The autoantibodies that block the activity of ADAMTS13 have..
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